How many clinical trials are running for tarlatamab?

ClinicalTrials.gov lists more than 16 phase 2–4 tarlatamab trials. This page tracks the 16 largest by enrolment: 9 phase 2, 7 phase 3, and 0 phase 4 among them, with 8 actively recruiting. Updated daily.

Are there clinical trials for Imdelltra?

Imdelltra is the brand name for tarlatamab, so tarlatamab trials on ClinicalTrials.gov cover it. ClinicalTrials.gov lists more than 16 phase 2–4 tarlatamab trials. This page tracks the 16 largest by enrolment: 9 phase 2, 7 phase 3, and 0 phase 4 among them, with 8 actively recruiting. Updated daily.

Where does this data come from?

All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.

Can I compare tarlatamab against other drugs?

Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.

Targeted & bispecific oncology · Live ClinicalTrials.gov data

Tarlatamab (Imdelltra) clinical trial pipeline

The timeline below tracks the 16 largest phase 2–4 tarlatamab (Imdelltra) trials on ClinicalTrials.gov by enrolment, 8 of them actively recruiting. The next phase 3 primary completion among them is expected Jul 2027. Refreshed daily. Add up to four competitors to compare pipelines side by side.

16+

Major trials tracked

Phase 3 trials

Actively recruiting

Jul 2027

Next phase 3 primary completion

3,782

Participants across trials

Amgen

Lead sponsor by trial count

tarlatamab (16)16 active2021–2039

Hide completed

tarlatamab

Key

Actual date

Anticipated

Forecast to primary completion

RecruitingActive, not recruitingNot yet recruiting

'21

'23

'25

'27

'29

'31

'33

'35

'37

'39

tarlatamab

DeLLphi-301P2

DeLLphi-304P3

DeLLphi-306P3

DeLLphi-305P3

DeLLphi-309P2

Clinical Trial for Safety and Effectiveness Evaluation of Tarlatamab (AMG757) With Etoposide, Carboplatin and Atezolizumab in Transformed Small Cell Lung Cancer Patients From Adenocarcinoma After EGFR TKI TreatmentP2

DeLLphi-312P3

Study of How Safe and Effective Tarlatamab is in Brain CancersP2

DeLLightP2

RAGNARP2

TARLANECP3

START-lungP2

DSC-NECP2

DeLLphi-315P3

REPLATP2

PrE0512P3

Upcoming readouts

15 ahead · tarlatamab

Select a trial to load its full ClinicalTrials.gov record.

Key tarlatamab trials

Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.

Trial	Title	Phase	Status	Primary completion
NCT07778316	DeLLphi-315: Phase 3 Trial of Tarlatamab (SC vs IV) in Extensive-Stage Small Cell Lung Cancer After Platinum …	Phase 3	Recruiting	Sept 2027
NCT07005128	DeLLphi-312: A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carbopla…	Phase 3	Recruiting	Jan 2029
NCT06937905	TARLANEC: Tarlatamab vs Standard of Care Chemotherapy in Patients With Pre-treated Advanced, Pulmonary or …	Phase 3	Recruiting	Feb 2029
NCT05740566	DeLLphi-304: Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer	Phase 3	Active, not recruiting	Jan 2025
NCT06211036	DeLLphi-305: Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage …	Phase 3	Active, not recruiting	Jul 2027
NCT06117774	DeLLphi-306: Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-…	Phase 3	Active, not recruiting	Apr 2030
NCT07637513	PrE0512: Tarlatamab and Durvalumab vs. Durvalumab Alone for Limited-Stage-Small Cell Lung Cancer	Phase 3	Not yet recruiting	Nov 2037
NCT06830694	Clinical Trial for Safety and Effectiveness Evaluation of Tarlatamab (AMG757) With Etoposide, Ca…	Phase 2	Recruiting	Mar 2027
NCT06776250	Study of How Safe and Effective Tarlatamab is in Brain Cancers	Phase 2	Recruiting	Mar 2028
NCT07061080	RAGNAR: Refractory Advanced diGestive Neuroendocrine Carcinomas Treated With tARlatamab	Phase 2	Recruiting	Dec 2028
NCT06893783	DeLLight: Efficacy and Safety Evaluation of Tarlatamab in Advanced Extrapulmonary Neuroendocrine Carcinoma…	Phase 2	Recruiting	Apr 2029
NCT07203053	START-lung: A Trial of Tarlatamab in Patients With Pretreated Extensive-stage Small Cell Lung Cancer (ES-SCL…	Phase 2	Recruiting	Oct 2029

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FAQ

How many clinical trials are running for tarlatamab?: ClinicalTrials.gov lists more than 16 phase 2–4 tarlatamab trials. This page tracks the 16 largest by enrolment: 9 phase 2, 7 phase 3, and 0 phase 4 among them, with 8 actively recruiting. Updated daily.
Are there clinical trials for Imdelltra?: Imdelltra is the brand name for tarlatamab, so tarlatamab trials on ClinicalTrials.gov cover it. ClinicalTrials.gov lists more than 16 phase 2–4 tarlatamab trials. This page tracks the 16 largest by enrolment: 9 phase 2, 7 phase 3, and 0 phase 4 among them, with 8 actively recruiting. Updated daily.
Where does this data come from?: All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare tarlatamab against other drugs?: Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.

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