Immuno-oncology checkpoint inhibitors · Live ClinicalTrials.gov data

Durvalumab (Imfinzi) clinical trial pipeline

The timeline below tracks the 16 largest phase 2–4 durvalumab (Imfinzi) trials on ClinicalTrials.gov by enrolment, 2 of them actively recruiting. The next phase 3 primary completion among them is expected Oct 2031. Refreshed daily. Add up to four competitors to compare pipelines side by side.

16+

Major trials tracked

6

Phase 3 trials

2

Actively recruiting

Oct 2031

Next phase 3 primary completion

6,449

Participants across trials

AstraZeneca

Lead sponsor by trial count

durvalumab (16)9 active2015–2033
durvalumab
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingCompletedUnknown status
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durvalumab
Phase II Study of MEDI4736, Tremelimumab, and MEDI4736 in Combination w/ Tremelimumab Squamous Cell Carcinoma of the Head and NeckP2
KESTRELP3
Multi-Arm Study to Test the Efficacy of Immunotherapeutic Agents in Multiple Sarcoma SubtypesP2
Durvalumab and Tremelimumab in Patients With Advanced Rare TumoursP2
HIMALAYAP3
IMMUCHECP2
CALLAP3
ORCHARDP2
ATOMICCP2
This Study is a Phase II Study of AZD6738 in Combination With Durvalumab in Patients With Solid Tumor (Cohort A (N=30): GC Who Have Failed Secondary Chemotherapy Treatments Regimen; Cohort B (B=30): Melanoma Patients Who Have Failed to IO)P2
Trial of Neoadjuvant Durvalumab Plus Docetaxel, Oxaliplatin, S-1 Followed by Surgery and Adjuvant Durvalumab Plus S-1 Chemotherapy in Potentially Resectable MMR Proficient Gastric or Gastroesophageal Junction AdenocarcinomaP2
IMMUWINP2
PACIFIC-9P3
EMERALD-3P3
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung CancerP3
Neoadjuvant Intra-tumor Double Immunotherapy for Lung Cancer.P2

Upcoming readouts

4 ahead · durvalumab

Select a trial to load its full ClinicalTrials.gov record.

Key durvalumab trials

Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.

TrialTitlePhaseStatusPrimary completion
NCT05624996Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advance…Phase 3RecruitingOct 2031
NCT03298451HIMALAYA: Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocel…Phase 3Active, not recruitingAug 2021
NCT05301842EMERALD-3: Evaluate Durvalumab and Tremelimumab +/- Lenvatinib in Combination With TACE in Patients With Lo…Phase 3Active, not recruitingFeb 2026
NCT05221840PACIFIC-9: A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab…Phase 3Active, not recruitingSept 2026
NCT02551159KESTREL: Phase III Open Label Study of MEDI 4736 With/Without Tremelimumab Versus Standard of Care (SOC) …Phase 3CompletedJul 2020
NCT03830866CALLA: Study of Durvalumab With Chemoradiotherapy for Women With Locally Advanced Cervical Cancer (CALL…Phase 3CompletedJan 2022
NCT06492421Neoadjuvant Intra-tumor Double Immunotherapy for Lung Cancer.Phase 2RecruitingDec 2028
NCT03944772ORCHARD: Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-L…Phase 2Active, not recruitingMay 2025
NCT04522544IMMUWIN: Durvalumab and Tremelimumab in Combination With Y-90 SIRT for Intermediate Stage HCCPhase 2Active, not recruitingJul 2027
NCT03833479ATOMICC: TSR-042 as Maintenance Therapy for Patients With High-risk Locally Advanced Cervical Cancer Afte…Phase 2Active, not recruitingJul 2028
NCT02319044Phase II Study of MEDI4736, Tremelimumab, and MEDI4736 in Combination w/ Tremelimumab Squamous C…Phase 2CompletedSept 2016
NCT02879162Durvalumab and Tremelimumab in Patients With Advanced Rare TumoursPhase 2CompletedJun 2021

Track durvalumab with ComplyRx

Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.

Track durvalumab

FAQ

How many clinical trials are running for durvalumab?
ClinicalTrials.gov lists more than 16 phase 2–4 durvalumab trials. This page tracks the 16 largest by enrolment: 10 phase 2, 6 phase 3, and 0 phase 4 among them, with 2 actively recruiting. Updated daily.
Are there clinical trials for Imfinzi?
Imfinzi is the brand name for durvalumab, so durvalumab trials on ClinicalTrials.gov cover it. ClinicalTrials.gov lists more than 16 phase 2–4 durvalumab trials. This page tracks the 16 largest by enrolment: 10 phase 2, 6 phase 3, and 0 phase 4 among them, with 2 actively recruiting. Updated daily.
Where does this data come from?
All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare durvalumab against other drugs?
Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.

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