Trials as lead sponsor
Most active programmes
The drugs appearing most often across Novo Nordisk's recently active trials. Comparator arms are excluded.
- Semaglutide22 trials
- Cagrilintide9 trials
- NNC0487-01119 trials
- Insulin icodec9 trials
- Concizumab6 trials
- Somapacitan5 trials
Upcoming readouts
Next primary completion dates among Novo Nordisk's active phase 2 and phase 3 trials. Dates are registry estimates and move often, which is exactly what the tracker watches.
- Jan 2027ONWARDS 11: A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar …Phase 3
- Jul 2027A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants…Phase 2
- Aug 2027Hibiscus 2: A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell DiseasePhase 3
- Sept 2027A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sug…Phase 2
- Oct 2027A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in …Phase 2
- Nov 20278212-Preserved: A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function…Phase 2
Top therapeutic areas
Conditions studied most often across Novo Nordisk's recently active trials.
- Obesity37 trials
- Overweight21 trials
- Diabetes Mellitus, Type 220 trials
- Haemophilia A6 trials
- Heart Failure5 trials
- Type 2 Diabetes4 trials
Novo Nordisk trials
The 50 most significant of Novo Nordisk's recently active trials, soonest estimated readout first.
Select any row for the full record; the change timeline unlocks with tracking.
| Trial | Phase | Stability | Status | Enrollment | Est. readout |
|---|---|---|---|---|---|
| Prevalence and Overlap of Cardiovascular, Kidney, and Metabolic Diseases in Korea: A Population-based StudyNCT07673822 | — | Not yet scored | OngoingEnrolling by invitation | 800,000 est. | 3 Aug 2026 |
| A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels Compared to Daily Basal Insulins in Adults With Type 2 DiabetesNCT07112339Insulin icodec | Phase 4 | Locked · track to reveal | OngoingRecruiting | 586 est. | 4 Aug 2026 |
| SPOTLIGHTA Two-armed Real-world Study of Ozempic (OW Semaglutide) to Evaluate Its Adherence and Persistence Compared With Other Anti-diabetic Drugs Among Adult T2DM Patients in ChinaNCT07456774 | — | Locked · track to reveal | OngoingEnrolling by invitation | 100,000 est. | 31 Aug 2026 |
| A Research Study to Compare Blood Levels of Two Different Versions of Cagrilintide in Adults With Excess Body WeightNCT07605052Cagrilintide B | Phase 1 | Locked · track to reveal | OngoingActive, not recruiting | 50 est. | 3 Sept 2026 |
| Patient Preferences in Treatment of Haemophilia A With and Without Inhibitors: a Discrete Choice Experiment in GermanyNCT07653139 | — | Not yet scored | OngoingNot yet recruiting | 150 est. | 26 Oct 2026 |
| A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or ObesityNCT07566390NNC0113-5840 | Phase 1 | Locked · track to reveal | OngoingRecruiting | 48 est. | 26 Nov 2026 |
| Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)NCT07225816Liraglutide | Phase 1 | Locked · track to reveal | OngoingRecruiting | 71 est. | 13 Dec 2026 |
| A Study Understanding How Much CDR132L Enters the Bloodstream After Injection Under the Skin Compared to Injection Into a Vein in Healthy ParticipantsNCT07656454CDR132L (i.v.) | Phase 1 | Not yet scored | OngoingRecruiting | 32 est. | 31 Dec 2026 |
| Database Linkage Study to Evaluate the Risk of Medullary Thyroid CarcinomaNCT07713901 | — | Not yet scored | OngoingEnrolling by invitation | 93,600,000 est. | 31 Dec 2026 |
| A Research Study to See How Insulin Icodec Helps People With Type 1 Diabetes Control Their Blood SugarNCT07160816Insulin icodec | — | Not yet scored | OngoingActive, not recruiting | 245 est. | 20 Jan 2027 |
| ONWARDS 11A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 DiabetesNCT07076199Insulin icodec | Phase 3 | Locked · track to reveal | OngoingRecruiting | 877 est. | 25 Jan 2027 |
| Management Concepts of Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) Among Chinese PhysiciansNCT07682363No treatment is given | — | Not yet scored | OngoingRecruiting | 470 est. | 23 Feb 2027 |
| A Research Study to See How Safe is Eptacog Alfa When Used to Stop Heavy Bleeding in Women After Giving Birth in IndiaNCT07157423Eptacog alfa (NovoSeven) | Phase 4 | Locked · track to reveal | OngoingRecruiting | 64 est. | 26 Mar 2027 |
| A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body WeightNCT07710768UBT251 | Phase 1 | Not yet scored | OngoingNot yet recruiting | 44 est. | 7 Apr 2027 |
| A Research Study Looking Into How Cagrilintide Influences Food Intake and Appetite in People With Overweight or ObesityNCT07557953Cagrilintide | Phase 1 | Locked · track to reveal | OngoingRecruiting | 120 est. | 13 Apr 2027 |
| A Research Study Looking Into How UBT251 Works With Birth Control Tablets and Emptying of the Stomach in Women With Excess Body Weight Not Able to Become PregnantNCT07710729UBT251 | Phase 1 | Not yet scored | OngoingNot yet recruiting | 40 est. | 27 Apr 2027 |
| RENEW 1Weight Loss in People Living With Overweight or Obesity Following Treatment With CagrilintideNCT07220642Cagrilintide | Phase 3 | Locked · track to reveal | OngoingActive, not recruiting | 300 est. | 11 May 2027 |
| A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or ObesityNCT07597018Cagrilintide D | Phase 1 | Locked · track to reveal | OngoingRecruiting | 234 est. | 28 May 2027 |
| HERMESA Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and InflammationNCT05636176Ziltivekimab | Phase 3 | Locked · track to reveal | OngoingActive, not recruiting | 4,899 est. | 2 Jul 2027 |
| A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With ObesityNCT07639021NNC0662-0419 | Phase 2 | Locked · track to reveal | OngoingRecruiting | 230 est. | 12 Jul 2027 |
| General Use-results Surveillance With Awiqli in Patients With Diabetes MellitusNCT06807190Insulin Icodec | — | Not yet scored | OngoingRecruiting | 630 est. | 31 Jul 2027 |
| A Study to See How Safe a New Medicine (NNC6022-0004) is in Healthy People and People Living With ObesityNCT07693868NNC6022-0004 | Phase 1 | Not yet scored | OngoingNot yet recruiting | 128 est. | 1 Aug 2027 |
| A Study to Evaluate the Safety of Exposure to Wegovy During PregnancyNCT05503927 | — | Locked · track to reveal | OngoingEnrolling by invitation | 2,701 est. | 15 Aug 2027 |
| A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 DiabetesNCT07357740CagriSema | Phase 2 | Locked · track to reveal | StoppedWithdrawn | 0 est. | 25 Aug 2027 |
| Hibiscus 2A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell DiseaseNCT06612268Etavopivat | Phase 3 | Locked · track to reveal | OngoingRecruiting | 408 est. | 27 Aug 2027 |
| REDEFINE 3REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood VesselsNCT05669755Cagrilintide | Phase 3 | Locked · track to reveal | OngoingActive, not recruiting | 7,101 est. | 1 Sept 2027 |
| A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 DiabetesNCT07415954NNC0662-0419 | Phase 2 | Locked · track to reveal | OngoingRecruiting | 270 est. | 3 Sept 2027 |
| A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 DiabetesNCT07668388UBT251 | Phase 2 | Locked · track to reveal | OngoingRecruiting | 300 est. | 4 Oct 2027 |
| 8212-PreservedA Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular HypertrophyNCT06979362CDR132L | Phase 2 | Locked · track to reveal | OngoingRecruiting | 200 est. | 16 Nov 2027 |
| Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse EventsNCT07607587Cagrilintide | Phase 1 | Locked · track to reveal | OngoingRecruiting | 114 est. | 19 Nov 2027 |
| A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body WeightNCT07357766Cagrisema | Phase 3 | Locked · track to reveal | StoppedWithdrawn | 0 est. | 29 Nov 2027 |
| A Research Study Looking Into Blood Levels of the Medicine NNC0487-0111 in the Body and How Well it is Tolerated in People With Reduced Liver Function and Normal Liver FunctionNCT07587710NNC0487-0111 | Phase 1 | Locked · track to reveal | OngoingNot yet recruiting | 35 est. | 1 Dec 2027 |
| ICOSWITCH REALResearch Study to Examine Blood Sugar Control, Treatment Satisfaction and Adherence in People With Type 2 Diabetes After Switching From Daily Basal Insulin to Once-weekly Insulin IcodecNCT07658417Insulin icodec | — | Not yet scored | OngoingNot yet recruiting | 216 est. | 1 Dec 2027 |
| ICOSWITCH REALA Research Study to Examine Blood Sugar Control, Treatment Satisfaction and Adherence in People With Type 2 Diabetes After Switching From Daily Basal Insulin to Once-weekly Insulin IcodecNCT07632404Insulin icodec | — | Not yet scored | OngoingNot yet recruiting | 214 est. | 1 Dec 2027 |
| A Study Following Males With Haemophilia B on Prophylaxis With Refixia/REBINYNNCT03745924Nonacog beta pegol | — | Not yet scored | OngoingEnrolling by invitation | 60 est. | 15 Dec 2027 |
| A Research Study Investigating the Effect of NNC0497-0040 in Healthy Participants, Participants With Overweight or Obesity, and Participants With Type 1 Diabetes With Overweight or ObesityNCT07578584NNC0497-0040 | Phase 1 | Locked · track to reveal | OngoingRecruiting | 146 est. | 18 Feb 2028 |
| A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightNCT07564414Cagrisema | Phase 3 | Locked · track to reveal | OngoingRecruiting | 2,500 est. | 23 Feb 2028 |
| A Research Study of a New Medicine, NNC9733-0001, in Healthy Participants and Participants With Type 2 DiabetesNCT07270731NNC9733-0001 | Phase 1 | Locked · track to reveal | OngoingRecruiting | 60 est. | 15 Mar 2028 |
| AMAZE 12AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight LossNCT07503210NNC0487-0111 | Phase 3 | Locked · track to reveal | OngoingRecruiting | 600 est. | 6 Jun 2028 |
| A Research Study to Evaluate the Safety of NNC1679-0001 When Given to Healthy Participants and Participants With T2DMNCT07570992NNC1679-0001 | Phase 1 | Locked · track to reveal | OngoingRecruiting | 58 est. | 25 Jun 2028 |
| AMAZE 4AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep ApnoeaNCT07571109NNC0487-0111 | Phase 3 | Locked · track to reveal | OngoingRecruiting | 300 est. | 26 Jun 2028 |
| FRONTIER4A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia ANCT05685238Mim8 | Phase 3 | Locked · track to reveal | OngoingRecruiting | 451 est. | 30 Jun 2028 |
| AMAZE 3AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep ApnoeaNCT07571005NNC0487-0111 | Phase 3 | Locked · track to reveal | OngoingRecruiting | 300 est. | 12 Jul 2028 |
| AMAZE 2AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose WeightNCT07533175NNC0487-0111 | Phase 3 | Locked · track to reveal | OngoingRecruiting | 630 est. | 7 Aug 2028 |
| AMAZE 5A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce PainNCT07481630NNC0487-0111 | Phase 3 | Locked · track to reveal | OngoingRecruiting | 400 est. | 14 Aug 2028 |
| AMAZE 6AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce PainNCT07509307NNC0487-0111 | Phase 3 | Locked · track to reveal | OngoingRecruiting | 400 est. | 14 Aug 2028 |
| PILLARA Two-year Prospective, Observational Study of Wegovy in Real-world Clinical PracticeNCT07055607Semaglutide | — | Locked · track to reveal | OngoingEnrolling by invitation | 1,250 est. | 15 Aug 2028 |
| AMAZE 7A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to SemaglutideNCT07668414Zenagamtide | Phase 3 | Locked · track to reveal | OngoingNot yet recruiting | 650 est. | 10 Oct 2028 |
| STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight LossNCT06571383Semaglutide | Phase 4 | Locked · track to reveal | OngoingActive, not recruiting | 500 est. | 15 Nov 2028 |
| AMAZE 13AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose WeightNCT07668401Zenagamtide | Phase 3 | Not yet scored | OngoingNot yet recruiting | 400 est. | 11 Jan 2029 |