Big pharma · NVO · 1,406 trials led

Novo Nordisk clinical trial pipeline

1,406 trials as lead sponsor, 62 recruiting now, 356 in phase 3. Live from ClinicalTrials.gov, updated daily.

  • Status changeStatus moved to completedWas recruiting · always alerts
  • Completion date movePrimary completion slipped 210 daysSlips and pull-ins of 30+ days
  • New trialNew trial registered in your scopeFirst posted within 30 days
  • Enrollment changeEnrollment grew to 1,200Moves of 15%+ or count finalised
  • Substantive record editPrimary endpoint redefined from 24 to 52 weeksRead overnight and flagged in plain English
View trials

Archive historyOct 2023 to Jul 2026

27 recorded changes across Novo Nordisk trials

Every status move, completion date shift and enrollment change ComplyRx has recorded across 17 of these trials. One is shown below.

Status changeStatus moved to recruiting from not yet recruitingNCT07557953 · recorded 1 Jun 2026
Track to read them

+23 more recorded changes · Track a drug to see every change the night it lands

Track semaglutide

Most active programmes

The drugs appearing most often across Novo Nordisk's recently active trials. Comparator arms are excluded.

  • Semaglutide22 trials
  • Cagrilintide9 trials
  • NNC0487-01119 trials
  • Insulin icodec9 trials
  • Concizumab6 trials
  • Somapacitan5 trials

Upcoming readouts

Next primary completion dates among Novo Nordisk's active phase 2 and phase 3 trials. Dates are registry estimates and move often, which is exactly what the tracker watches.

Top therapeutic areas

Conditions studied most often across Novo Nordisk's recently active trials.

  • Obesity37 trials
  • Overweight21 trials
  • Diabetes Mellitus, Type 220 trials
  • Haemophilia A6 trials
  • Heart Failure5 trials
  • Type 2 Diabetes4 trials

Novo Nordisk trials

The 50 most significant of Novo Nordisk's recently active trials, soonest estimated readout first.
Select any row for the full record; the change timeline unlocks with tracking.

TrialPhaseStabilityStatusEnrollmentEst. readout
Prevalence and Overlap of Cardiovascular, Kidney, and Metabolic Diseases in Korea: A Population-based StudyNCT07673822Not yet scoredOngoingEnrolling by invitation800,000 est.3 Aug 2026
A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels Compared to Daily Basal Insulins in Adults With Type 2 DiabetesNCT07112339Insulin icodecPhase 4Locked · track to revealOngoingRecruiting586 est.4 Aug 2026
SPOTLIGHTA Two-armed Real-world Study of Ozempic (OW Semaglutide) to Evaluate Its Adherence and Persistence Compared With Other Anti-diabetic Drugs Among Adult T2DM Patients in ChinaNCT07456774Locked · track to revealOngoingEnrolling by invitation100,000 est.31 Aug 2026
A Research Study to Compare Blood Levels of Two Different Versions of Cagrilintide in Adults With Excess Body WeightNCT07605052Cagrilintide BPhase 1Locked · track to revealOngoingActive, not recruiting50 est.3 Sept 2026
Patient Preferences in Treatment of Haemophilia A With and Without Inhibitors: a Discrete Choice Experiment in GermanyNCT07653139Not yet scoredOngoingNot yet recruiting150 est.26 Oct 2026
A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or ObesityNCT07566390NNC0113-5840Phase 1Locked · track to revealOngoingRecruiting48 est.26 Nov 2026
Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)NCT07225816LiraglutidePhase 1Locked · track to revealOngoingRecruiting71 est.13 Dec 2026
A Study Understanding How Much CDR132L Enters the Bloodstream After Injection Under the Skin Compared to Injection Into a Vein in Healthy ParticipantsNCT07656454CDR132L (i.v.)Phase 1Not yet scoredOngoingRecruiting32 est.31 Dec 2026
Database Linkage Study to Evaluate the Risk of Medullary Thyroid CarcinomaNCT07713901Not yet scoredOngoingEnrolling by invitation93,600,000 est.31 Dec 2026
A Research Study to See How Insulin Icodec Helps People With Type 1 Diabetes Control Their Blood SugarNCT07160816Insulin icodecNot yet scoredOngoingActive, not recruiting245 est.20 Jan 2027
ONWARDS 11A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 DiabetesNCT07076199Insulin icodecPhase 3Locked · track to revealOngoingRecruiting877 est.25 Jan 2027
Management Concepts of Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) Among Chinese PhysiciansNCT07682363No treatment is givenNot yet scoredOngoingRecruiting470 est.23 Feb 2027
A Research Study to See How Safe is Eptacog Alfa When Used to Stop Heavy Bleeding in Women After Giving Birth in IndiaNCT07157423Eptacog alfa (NovoSeven)Phase 4Locked · track to revealOngoingRecruiting64 est.26 Mar 2027
A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body WeightNCT07710768UBT251Phase 1Not yet scoredOngoingNot yet recruiting44 est.7 Apr 2027
A Research Study Looking Into How Cagrilintide Influences Food Intake and Appetite in People With Overweight or ObesityNCT07557953CagrilintidePhase 1Locked · track to revealOngoingRecruiting120 est.13 Apr 2027
A Research Study Looking Into How UBT251 Works With Birth Control Tablets and Emptying of the Stomach in Women With Excess Body Weight Not Able to Become PregnantNCT07710729UBT251Phase 1Not yet scoredOngoingNot yet recruiting40 est.27 Apr 2027
RENEW 1Weight Loss in People Living With Overweight or Obesity Following Treatment With CagrilintideNCT07220642CagrilintidePhase 3Locked · track to revealOngoingActive, not recruiting300 est.11 May 2027
A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or ObesityNCT07597018Cagrilintide DPhase 1Locked · track to revealOngoingRecruiting234 est.28 May 2027
HERMESA Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and InflammationNCT05636176ZiltivekimabPhase 3Locked · track to revealOngoingActive, not recruiting4,899 est.2 Jul 2027
A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With ObesityNCT07639021NNC0662-0419Phase 2Locked · track to revealOngoingRecruiting230 est.12 Jul 2027
General Use-results Surveillance With Awiqli in Patients With Diabetes MellitusNCT06807190Insulin IcodecNot yet scoredOngoingRecruiting630 est.31 Jul 2027
A Study to See How Safe a New Medicine (NNC6022-0004) is in Healthy People and People Living With ObesityNCT07693868NNC6022-0004Phase 1Not yet scoredOngoingNot yet recruiting128 est.1 Aug 2027
A Study to Evaluate the Safety of Exposure to Wegovy During PregnancyNCT05503927Locked · track to revealOngoingEnrolling by invitation2,701 est.15 Aug 2027
A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 DiabetesNCT07357740CagriSemaPhase 2Locked · track to revealStoppedWithdrawn0 est.25 Aug 2027
Hibiscus 2A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell DiseaseNCT06612268EtavopivatPhase 3Locked · track to revealOngoingRecruiting408 est.27 Aug 2027
REDEFINE 3REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood VesselsNCT05669755CagrilintidePhase 3Locked · track to revealOngoingActive, not recruiting7,101 est.1 Sept 2027
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 DiabetesNCT07415954NNC0662-0419Phase 2Locked · track to revealOngoingRecruiting270 est.3 Sept 2027
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 DiabetesNCT07668388UBT251Phase 2Locked · track to revealOngoingRecruiting300 est.4 Oct 2027
8212-PreservedA Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular HypertrophyNCT06979362CDR132LPhase 2Locked · track to revealOngoingRecruiting200 est.16 Nov 2027
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse EventsNCT07607587CagrilintidePhase 1Locked · track to revealOngoingRecruiting114 est.19 Nov 2027
A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body WeightNCT07357766CagrisemaPhase 3Locked · track to revealStoppedWithdrawn0 est.29 Nov 2027
A Research Study Looking Into Blood Levels of the Medicine NNC0487-0111 in the Body and How Well it is Tolerated in People With Reduced Liver Function and Normal Liver FunctionNCT07587710NNC0487-0111Phase 1Locked · track to revealOngoingNot yet recruiting35 est.1 Dec 2027
ICOSWITCH REALResearch Study to Examine Blood Sugar Control, Treatment Satisfaction and Adherence in People With Type 2 Diabetes After Switching From Daily Basal Insulin to Once-weekly Insulin IcodecNCT07658417Insulin icodecNot yet scoredOngoingNot yet recruiting216 est.1 Dec 2027
ICOSWITCH REALA Research Study to Examine Blood Sugar Control, Treatment Satisfaction and Adherence in People With Type 2 Diabetes After Switching From Daily Basal Insulin to Once-weekly Insulin IcodecNCT07632404Insulin icodecNot yet scoredOngoingNot yet recruiting214 est.1 Dec 2027
A Study Following Males With Haemophilia B on Prophylaxis With Refixia/REBINYNNCT03745924Nonacog beta pegolNot yet scoredOngoingEnrolling by invitation60 est.15 Dec 2027
A Research Study Investigating the Effect of NNC0497-0040 in Healthy Participants, Participants With Overweight or Obesity, and Participants With Type 1 Diabetes With Overweight or ObesityNCT07578584NNC0497-0040Phase 1Locked · track to revealOngoingRecruiting146 est.18 Feb 2028
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightNCT07564414CagrisemaPhase 3Locked · track to revealOngoingRecruiting2,500 est.23 Feb 2028
A Research Study of a New Medicine, NNC9733-0001, in Healthy Participants and Participants With Type 2 DiabetesNCT07270731NNC9733-0001Phase 1Locked · track to revealOngoingRecruiting60 est.15 Mar 2028
AMAZE 12AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight LossNCT07503210NNC0487-0111Phase 3Locked · track to revealOngoingRecruiting600 est.6 Jun 2028
A Research Study to Evaluate the Safety of NNC1679-0001 When Given to Healthy Participants and Participants With T2DMNCT07570992NNC1679-0001Phase 1Locked · track to revealOngoingRecruiting58 est.25 Jun 2028
AMAZE 4AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep ApnoeaNCT07571109NNC0487-0111Phase 3Locked · track to revealOngoingRecruiting300 est.26 Jun 2028
FRONTIER4A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia ANCT05685238Mim8Phase 3Locked · track to revealOngoingRecruiting451 est.30 Jun 2028
AMAZE 3AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep ApnoeaNCT07571005NNC0487-0111Phase 3Locked · track to revealOngoingRecruiting300 est.12 Jul 2028
AMAZE 2AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose WeightNCT07533175NNC0487-0111Phase 3Locked · track to revealOngoingRecruiting630 est.7 Aug 2028
AMAZE 5A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce PainNCT07481630NNC0487-0111Phase 3Locked · track to revealOngoingRecruiting400 est.14 Aug 2028
AMAZE 6AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce PainNCT07509307NNC0487-0111Phase 3Locked · track to revealOngoingRecruiting400 est.14 Aug 2028
PILLARA Two-year Prospective, Observational Study of Wegovy in Real-world Clinical PracticeNCT07055607SemaglutideLocked · track to revealOngoingEnrolling by invitation1,250 est.15 Aug 2028
AMAZE 7A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to SemaglutideNCT07668414ZenagamtidePhase 3Locked · track to revealOngoingNot yet recruiting650 est.10 Oct 2028
STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight LossNCT06571383SemaglutidePhase 4Locked · track to revealOngoingActive, not recruiting500 est.15 Nov 2028
AMAZE 13AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose WeightNCT07668401ZenagamtidePhase 3Not yet scoredOngoingNot yet recruiting400 est.11 Jan 2029
View all trials1,406

Track your drug now for free

We check every one of its trials daily and tell you what moved.

  • Status changeStatus moved to completedWas recruiting · always alerts
  • Completion date movePrimary completion slipped 210 daysSlips and pull-ins of 30+ days
  • New trialNew trial registered in your scopeFirst posted within 30 days
  • Enrollment changeEnrollment grew to 1,200Moves of 15%+ or count finalised
  • Substantive record editPrimary endpoint redefined from 24 to 52 weeksRead overnight and flagged in plain English
US registryClinicalTrials.gov
EU registryCTIS · Soon
1,406

Trials as lead sponsor

62

Recruiting now

356

Phase 3 trials

121

Phase 2 trials

472

Phase 1 trials

104

Phase 4 trials