Phase 2–4 trials
KRAS inhibitors · Live ClinicalTrials.gov data
Divarasib clinical trial pipeline
ClinicalTrials.gov lists 7 phase 2–4 trials for divarasib, 3 of them actively recruiting. The next phase 3 primary completion among them is expected Nov 2028. Refreshed daily — add up to four competitors to compare pipelines side by side.
7
4
Phase 3 trials
3
Actively recruiting
Nov 2028
Next phase 3 primary completion
3,457
Participants across trials
Hoffmann-La Roche
Lead sponsor by trial count
divarasib (7)7 active2017–2034
divarasib
'17
'19
'21
'23
'25
'27
'29
'31
'33
divarasib
B-FASTP2
NAUTIKA1P2
Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform StudyP2
UmbrellaMAXP3
Krascendo 1P3
Krascendo 2P3
KRASCENDO 3P3
Upcoming readouts
6 ahead · divarasib
Select a trial to load its full ClinicalTrials.gov record.
Key divarasib trials
Top 7 of the 7 registered phase 2–4 trials, ordered by phase and status. Each links to its full ClinicalTrials.gov record.
| Trial | Title | Phase | Status | Primary completion |
|---|---|---|---|---|
| NCT06793215 | Krascendo 2 — A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed … | Phase 3 | Recruiting | Nov 2028 |
| NCT05862285 | UmbrellaMAX — A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Stud… | Phase 3 | Recruiting | Mar 2033 |
| NCT06497556 | Krascendo 1 — A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Pre… | Phase 3 | Active, not recruiting | May 2026 |
| NCT07541170 | KRASCENDO 3 — A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy … | Phase 3 | Not yet recruiting | Jan 2032 |
| NCT04302025 | NAUTIKA1 — A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell … | Phase 2 | Recruiting | Nov 2026 |
| NCT03178552 | B-FAST — A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With… | Phase 2 | Active, not recruiting | Oct 2026 |
| NCT04589845 | Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study | Phase 2 | Active, not recruiting | Sept 2032 |
Related drug pipelines
FAQ
- How many clinical trials are running for divarasib?
- ClinicalTrials.gov currently lists 7 phase 2–4 divarasib trials: 3 phase 2, 4 phase 3, and 0 phase 4. 3 are actively recruiting.
- Where does this data come from?
- All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
- Can I compare divarasib against other drugs?
- Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
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