KRAS inhibitors · Live ClinicalTrials.gov data

Divarasib clinical trial pipeline

ClinicalTrials.gov lists 7 phase 2–4 trials for divarasib, 3 of them actively recruiting. The next phase 3 primary completion among them is expected Nov 2028. Refreshed daily — add up to four competitors to compare pipelines side by side.

7

Phase 2–4 trials

4

Phase 3 trials

3

Actively recruiting

Nov 2028

Next phase 3 primary completion

3,457

Participants across trials

Hoffmann-La Roche

Lead sponsor by trial count

divarasib (7)7 active20172034
divarasib
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingNot yet recruiting
'17
'19
'21
'23
'25
'27
'29
'31
'33
divarasib
B-FASTP2
NAUTIKA1P2
Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform StudyP2
UmbrellaMAXP3
Krascendo 1P3
Krascendo 2P3
KRASCENDO 3P3

Upcoming readouts

6 ahead · divarasib

Select a trial to load its full ClinicalTrials.gov record.

Key divarasib trials

Top 7 of the 7 registered phase 2–4 trials, ordered by phase and status. Each links to its full ClinicalTrials.gov record.

TrialTitlePhaseStatusPrimary completion
NCT06793215Krascendo 2 — A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed …Phase 3RecruitingNov 2028
NCT05862285UmbrellaMAX — A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Stud…Phase 3RecruitingMar 2033
NCT06497556Krascendo 1 — A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Pre…Phase 3Active, not recruitingMay 2026
NCT07541170KRASCENDO 3 — A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy …Phase 3Not yet recruitingJan 2032
NCT04302025NAUTIKA1 — A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell …Phase 2RecruitingNov 2026
NCT03178552B-FAST — A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With…Phase 2Active, not recruitingOct 2026
NCT04589845Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform StudyPhase 2Active, not recruitingSept 2032

FAQ

How many clinical trials are running for divarasib?
ClinicalTrials.gov currently lists 7 phase 2–4 divarasib trials: 3 phase 2, 4 phase 3, and 0 phase 4. 3 are actively recruiting.
Where does this data come from?
All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare divarasib against other drugs?
Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
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