16+
Major trials tracked
Immuno-oncology checkpoint inhibitors · Live ClinicalTrials.gov data
Pembrolizumab (Keytruda) clinical trial pipeline
The timeline below tracks the 16 largest phase 2–4 pembrolizumab (Keytruda) trials on ClinicalTrials.gov by enrolment, 4 of them actively recruiting. The next phase 3 primary completion among them is expected Dec 2026. Refreshed daily. Add up to four competitors to compare pipelines side by side.
6
Phase 3 trials
4
Actively recruiting
Dec 2026
Next phase 3 primary completion
5,778
Participants across trials
Merck Sharp & Dohme LLC
Lead sponsor by trial count
pembrolizumab (16)13 active2015–2034
pembrolizumab
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pembrolizumab
Pembrolizumab and Epacadostat in Patients With Thymic CarcinomaP2
A Randomized Phase II Study Of Eribulin Mesylate With or Without Pembrolizumab For Metastatic Hormone Receptor Positive Breast CancerP2
Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)P3
TACTI-002P2
LEAP-001P3
Pembrolizumab, Lenvatinib and Chemotherapy After TKIs in NSCLCP2
SEAMARKP2
Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and NeckP2
Pembro-SRTP2
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric AdenocarcinomaP3
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast CancerP3
Neoadjuvant Intra-tumor Double Immunotherapy for Lung Cancer.P2
Pharmacokinetic Study of QL2107 Versus Keytruda® for Adjuvant Therapy of Non-Small Cell Lung Cancer (NSCLC)P3
Omega-3 Supplementation and Immunotherapy in Gastric Cancer: A Phase II TrialP2
A Study to Assess Adverse Events, Change in Disease Activity and Optimal Dose of Intravenous (IV) Telisotuzumab Adizutecan With IV Pembrolizumab for First-Line Treatment of Adult Participants With Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaP2
Efficacy and Safety of a Repurposed Drug Added to the Combination of Len Plus Pem in Advanced Endometrial CancerP3
Upcoming readouts
7 ahead · pembrolizumab
Select a trial to load its full ClinicalTrials.gov record.
Key pembrolizumab trials
Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.
Track pembrolizumab with ComplyRx
Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.
Related drug pipelines
FAQ
- How many clinical trials are running for pembrolizumab?
- ClinicalTrials.gov lists more than 16 phase 2–4 pembrolizumab trials. This page tracks the 16 largest by enrolment: 10 phase 2, 6 phase 3, and 0 phase 4 among them, with 4 actively recruiting. Updated daily.
- Are there clinical trials for Keytruda?
- Keytruda is the brand name for pembrolizumab, so pembrolizumab trials on ClinicalTrials.gov cover it. ClinicalTrials.gov lists more than 16 phase 2–4 pembrolizumab trials. This page tracks the 16 largest by enrolment: 10 phase 2, 6 phase 3, and 0 phase 4 among them, with 4 actively recruiting. Updated daily.
- Where does this data come from?
- All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
- Can I compare pembrolizumab against other drugs?
- Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
