Antibody-drug conjugates · Live ClinicalTrials.gov data

Sacituzumab govitecan (Trodelvy) clinical trial pipeline

The timeline below tracks the 16 largest phase 2–4 sacituzumab govitecan (Trodelvy) trials on ClinicalTrials.gov by enrolment, 8 of them actively recruiting. The next phase 3 primary completion among them is expected Dec 2026. Refreshed daily. Add up to four competitors to compare pipelines side by side.

16+

Major trials tracked

6

Phase 3 trials

8

Actively recruiting

Dec 2026

Next phase 3 primary completion

7,156

Participants across trials

Gilead Sciences

Lead sponsor by trial count

sacituzumab govitecan (16)16 active2019–2034
sacituzumab govitecan
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingNot yet recruiting
'19
'21
'23
'25
'27
'29
'31
'33
sacituzumab govitecan
TROPiCS-03P2
SASCIAP3
Asian Study of Sacituzumab Govitecan (IMMU-132) in HR+/HER2- Metastatic Breast Cancer (MBC)P3
Scalp Cooling in MBCP2
A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)P2
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)P3
Genomics Guided Targeted Post-neoadjuvant Therapy in Patients With Early Breast Cancer (COGNITION-GUIDE)P2
Circulating Tumor DNA to Guide Changes in Standard of Care ChemotherapyP2
ASCENT-GYN-01P3
Precision Medicine Trial Based on Molecular Matching Therapy for Patients With Standard Treatment ExhaustionP2
Optimal Application Timing of ADC Drugs for Advanced Breast CancerP2
A Study of Sacituzumab Govitecan Plus Toripalimab Versus Toripalimab Plus Nab-Paclitaxel in PD-L1 Positive Advanced TNBCP2
OASISP2
YL202 Versus Treatment of Physician's Choice in Patients With HR+/HER2- Breast CancerP3
ADAPT-TN-IVP3
PROBEP2

Upcoming readouts

13 ahead · sacituzumab govitecan

Select a trial to load its full ClinicalTrials.gov record.

Key sacituzumab govitecan trials

Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.

TrialTitlePhaseStatusPrimary completion
NCT05633654Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in …Phase 3RecruitingJun 2027
NCT07461454YL202 Versus Treatment of Physician's Choice in Patients With HR+/HER2- Breast CancerPhase 3RecruitingDec 2027
NCT04639986Asian Study of Sacituzumab Govitecan (IMMU-132) in HR+/HER2- Metastatic Breast Cancer (MBC)Phase 3Active, not recruitingDec 2026
NCT04595565SASCIA: Sacituzumab Govitecan in Primary HER2-negative Breast CancerPhase 3Active, not recruitingMar 2027
NCT06486441ASCENT-GYN-01: Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endom…Phase 3Active, not recruitingJun 2029
NCT07178730ADAPT-TN-IV: NeoAdjuvant Therapy Comparing Sacituzumab Govitecan+Pembrolizumab vs. SoC Chemotherapy in Clinic…Phase 3Not yet recruitingMar 2033
NCT07657130Optimal Application Timing of ADC Drugs for Advanced Breast CancerPhase 2RecruitingJun 2026
NCT06739395Precision Medicine Trial Based on Molecular Matching Therapy for Patients With Standard Treatmen…Phase 2RecruitingDec 2026
NCT04986579Scalp Cooling in MBCPhase 2RecruitingJun 2028
NCT05770531Circulating Tumor DNA to Guide Changes in Standard of Care ChemotherapyPhase 2RecruitingAug 2028
NCT05332561Genomics Guided Targeted Post-neoadjuvant Therapy in Patients With Early Breast Cancer (COGNITIO…Phase 2RecruitingMar 2030
NCT07259226OASIS: Optimal Methods to Characterize ADC Resistance in Solid Tumors and Identify Clinically Useful Bi…Phase 2RecruitingNov 2030

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FAQ

How many clinical trials are running for sacituzumab govitecan?
ClinicalTrials.gov lists more than 16 phase 2–4 sacituzumab govitecan trials. This page tracks the 16 largest by enrolment: 10 phase 2, 6 phase 3, and 0 phase 4 among them, with 8 actively recruiting. Updated daily.
Are there clinical trials for Trodelvy?
Trodelvy is the brand name for sacituzumab govitecan, so sacituzumab govitecan trials on ClinicalTrials.gov cover it. ClinicalTrials.gov lists more than 16 phase 2–4 sacituzumab govitecan trials. This page tracks the 16 largest by enrolment: 10 phase 2, 6 phase 3, and 0 phase 4 among them, with 8 actively recruiting. Updated daily.
Where does this data come from?
All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare sacituzumab govitecan against other drugs?
Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.

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