16+
Major trials tracked
Antibody-drug conjugates · Live ClinicalTrials.gov data
Trastuzumab deruxtecan (Enhertu) clinical trial pipeline
The timeline below tracks the 16 largest phase 2–4 trastuzumab deruxtecan (Enhertu) trials on ClinicalTrials.gov by enrolment, 10 of them actively recruiting. The next phase 3 primary completion among them is expected Jun 2028. Refreshed daily. Add up to four competitors to compare pipelines side by side.
4
Phase 3 trials
10
Actively recruiting
Jun 2028
Next phase 3 primary completion
8,686
Participants across trials
AstraZeneca
Lead sponsor by trial count
trastuzumab deruxtecan (16)14 active2016–2030
trastuzumab deruxtecan
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trastuzumab deruxtecan
TAPURP2
DS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing Gastric Cancer [DESTINY-Gastric01]P2
DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02]P3
DG-03P2
DPT01P2
Scalp Cooling in MBCP2
A Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 MutationsP3
Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)P2
A Study of T-DXd as Monotherapy or in Combination With Anti-cancer Agents in Patients With Selected HER2-expressing TumorsP2
DESTINY-BTC01P3
TRADE DXdP2
Perioperative Therapies in Locally Advanced Unresectable Gastric CancerP2
Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction CancerP3
Optimal Application Timing of ADC Drugs for Advanced Breast CancerP2
ASPEN-09-03P2
A Trial of Trastuzumab Rezetecan in Unresectable Locally Recurrent/Metastatic Breast CancerP2
Upcoming readouts
11 ahead · trastuzumab deruxtecan
Select a trial to load its full ClinicalTrials.gov record.
Key trastuzumab deruxtecan trials
Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.
Track trastuzumab deruxtecan with ComplyRx
Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.
Related drug pipelines
FAQ
- How many clinical trials are running for trastuzumab deruxtecan?
- ClinicalTrials.gov lists more than 16 phase 2–4 trastuzumab deruxtecan trials. This page tracks the 16 largest by enrolment: 12 phase 2, 4 phase 3, and 0 phase 4 among them, with 10 actively recruiting. Updated daily.
- Are there clinical trials for Enhertu?
- Enhertu is the brand name for trastuzumab deruxtecan, so trastuzumab deruxtecan trials on ClinicalTrials.gov cover it. ClinicalTrials.gov lists more than 16 phase 2–4 trastuzumab deruxtecan trials. This page tracks the 16 largest by enrolment: 12 phase 2, 4 phase 3, and 0 phase 4 among them, with 10 actively recruiting. Updated daily.
- Where does this data come from?
- All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
- Can I compare trastuzumab deruxtecan against other drugs?
- Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
