Big pharma · ABBV · 2,088 trials led

AbbVie clinical trial pipeline

2,088 trials as lead sponsor, 117 recruiting now, 599 in phase 3. Live from ClinicalTrials.gov, updated daily.

  • Status changeStatus moved to completedWas recruiting · always alerts
  • Completion date movePrimary completion slipped 210 daysSlips and pull-ins of 30+ days
  • New trialNew trial registered in your scopeFirst posted within 30 days
  • Enrollment changeEnrollment grew to 1,200Moves of 15%+ or count finalised
  • Substantive record editPrimary endpoint redefined from 24 to 52 weeksRead overnight and flagged in plain English
View trials

Archive historyApr 2023 to Sept 2026

103 recorded changes across AbbVie trials

Every status move, completion date shift and enrollment change ComplyRx has recorded across 34 of these trials. One is shown below.

Status changeStatus moved to recruiting from not yet recruitingNCT07071532 · recorded 17 Sept 2026
Track to read them

+99 more recorded changes · Track a drug to see every change the night it lands

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Most active programmes

The drugs appearing most often across AbbVie's recently active trials. Comparator arms are excluded.

  • Carboplatin9 trials
  • Telisotuzumab Adizutecan6 trials
  • Venetoclax6 trials
  • Risankizumab6 trials
  • Bevacizumab5 trials
  • Upadacitinib5 trials

Upcoming readouts

Next primary completion dates among AbbVie's active phase 2 and phase 3 trials. Dates are registry estimates and move often, which is exactly what the tracker watches.

Top therapeutic areas

Conditions studied most often across AbbVie's recently active trials.

  • Non-Small Cell Lung Cancer5 trials
  • Acute Myeloid Leukemia4 trials
  • Ulcerative Colitis4 trials
  • Atopic Dermatitis4 trials
  • Crohn's Disease3 trials
  • Ovarian Cancer3 trials

AbbVie pipeline by phase

The main study drugs across 211 active trials AbbVie leads on ClinicalTrials.gov. Each drug sits in the highest phase among its currently active trials, which can be lower than a phase it has already completed.

Phase 328 drugs

AbbVie phase 3 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
Upadacitinib165Jan 2027 est.NCT07772492 · NCT07023302 · NCT06701331
Telisotuzumab AdizutecanABBV-400158Dec 2026 est.NCT07525206 · NCT06614192 · NCT07769502
Risankizumab116Jan 2027 est.NCT07071519 · NCT06880744 · NCT05995353
EtentamigTNB-383B104Dec 2027 est.NCT07793422 · NCT07728188 · NCT06158841
Lutikizumab73Dec 2026 est.NCT06468228 · NCT06972446 · NCT06865105
Atogepant53Mar 2028 est.NCT06810505 · NCT06806293 · NCT05711394
Surabgene LomparvovecRGX-31452Oct 2026 est.NCT07007065 · NCT05407636 · NCT07592273
Ubrogepant42Oct 2026 est.NCT06417775 · NCT05127954 · NCT05125302
ABBV-70632Nov 2027 est.NCT07365241 · NCT07155174 · NCT05599984
Telisotuzumab vedotin32Feb 2028 est.NCT04928846 · NCT06568939 · NCT03539536
Adalimumab21NCT06100744 · NCT02629159
Navitoclax2Dec 2026 est.NCT04468984 · NCT04041050
25mg Eluxadoline1Dec 2032 est.NCT04880876
ABBV-14801Dec 2029 est.NCT07756645
ABBV-4441NCT07284381
ARTIA Reconstructive Tissue Matrix11Feb 2031 est.NCT06575192
Cariprazine11Mar 2027 est.NCT04777357
Elagolix1Jul 2027 est.NCT04333576
ELAPR002f Injectable Gel11Nov 2029 est.NCT07207369
HArmonyCa Lidocaine Injectable Gel1NCT07032597
Mirvetuximab soravtansine plus Bevacizumab1Apr 2027 est.NCT05445778
NOA LIFT11Aug 2028 est.NCT07794878
NOA VOLUME11Jul 2029 est.NCT06734351
Risankizumab IV1Feb 2029 est.NCT03105102
Risankizumab SC1Mar 2027 est.NCT06063967
Upadacitinib (ABT-494)1Jul 2027 est.NCT03006068
Upadacitinib 15mg Dose11NCT06389136
XEN63 Glaucoma Treatment System11Nov 2028 est.NCT06822738

Phase 219 drugs

AbbVie phase 2 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
Livmoniplimab52Feb 2027 est.NCT06632951 · NCT06236438 · NCT06109272
ABBV-93243Nov 2026 est.NCT07220460 · NCT06846320 · NCT07071532
Mirvetuximab soravtansine42Nov 2026 est.NCT07059845 · NCT06682988 · NCT06365853
ABBV-29532Jan 2027 est.NCT07752979 · NCT07514260 · NCT07291232
AGN-15158622Oct 2026 est.NCT07730554 · NCT07756580
AGN-151607-DP22Sept 2028 est.NCT07673107 · NCT07226791
Emraclidine22Dec 2026 est.NCT07145918 · NCT07219030
Icalcaprant22Sept 2027 est.NCT07276997 · NCT06696755
IMGN15121Feb 2027 est.NCT07024784 · NCT05527184
Pivekimab Sunirine22Apr 2028 est.NCT07581002 · NCT07306832
ABBV-14211Sept 2029 est.NCT07230288
Armour Thyroid11Sept 2027 est.NCT06345339
Budigalimab1Nov 2026 est.NCT05822752
Carfilzomib1Jun 2027 est.NCT02899052
Eluxadoline11Dec 2026 est.NCT03339128

Phase 135 drugs

AbbVie phase 1 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
ABBV-31921Feb 2027 est.NCT06977724 · NCT05512390
ABBV-9272Mar 2027 est.NCT03893955 · NCT02988960
ABBV-1011Mar 2031 est.NCT05753501
ABBV-104211NCT07222709
ABBV-145111Apr 2027 est.NCT07570147
ABBV-175811Oct 2030 est.NCT07599670
ABBV-24311May 2027 est.NCT07306754
ABBV-2531Dec 2029 est.NCT07807956
ABBV-2911Apr 2027 est.NCT06667687
ABBV-31311Feb 2028 est.NCT07673120

Phase 43 drugs

AbbVie phase 4 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
Venetoclax83Nov 2026 est.NCT07044687 · NCT05144243 · NCT06428019
OnabotulinumtoxinA1Jun 2027 est.NCT07794891
XEN45 Glaucoma Treatment System1Jul 2030 est.NCT05821855

Combination backbones Azacitidine (2 trials), Dexamethasone (2 trials), Carboplatin (1 trial). Established agents these trials combine with, listed separately from the drugs under study.

Derived from 211 active trials AbbVie leads; 188 name an intervention, folding into 85 phased drugs. This is ComplyRx's reading of the registry, not AbbVie's own pipeline disclosure.

AbbVie trials

The 50 most significant of AbbVie's recently active trials, soonest estimated readout first.
Select any row for the full record; the change timeline unlocks with tracking.

TrialPhaseStabilityStatusEnrollmentEst. readout
A Study to Assess the Safety and Efficacy of AGN-151586 Injections for the Treatment of Moderate to Severe Forehead Lines (FHL) in Adult ParticipantsNCT07730554AGN-151586Phase 2Not yet scoredOngoingRecruiting80 est.Oct 2026
Study to Assess How Different Oral Formulations of Ubrogepant Move Through the Body in Healthy Adult ParticipantsNCT07680686UbrogepantPhase 1Not yet scoredOngoingRecruiting52 est.Oct 2026
ESVECOA Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Receiving Oral Venetoclax Tablets in Combination With Subcutaneously (SC) or Intravenously (IV) Injected Azacitidine in ColombiaNCT05587049Not yet scoredOngoingRecruiting70 est.Nov 2026
A Study to Assess the Adverse Events and How Oral Emraclidine Moves Through the Body of Healthy Elderly Adult ParticipantsNCT07219030EmraclidinePhase 1Locked · track to revealOngoingRecruiting52 est.Dec 2026
IntrepidA Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis SuppurativaNCT06468228LutikizumabPhase 3Locked · track to revealOngoingActive, not recruiting1,400 est.Dec 2026
ONIROSA Study to Assess Change in Sleep Disturbances of Adult Participants With Advanced Parkinson's Disease Receiving Subcutaneous Foslevodopa/FoscarbidopaNCT07284342Not yet scoredOngoingRecruiting103 est.Jan 2027
A Study to Assess Adverse Events, Tolerability, and Pharmacokinetics of Subcutaneous Injections of ABBV-295 in Healthy Adult Japanese Participants With Overweight or Obesity.NCT07514260ABBV-295Phase 1Locked · track to revealOngoingActive, not recruiting24 est.Jan 2027
A Study to Assess Adverse Events and How Oral ABBV-932 Moves Through the Body When Given With Oral Itraconazole in Adult Participants With Bipolar DisorderNCT07071532ABBV-932Phase 1Locked · track to revealOngoingRecruiting20 est.Feb 2027
A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha ExpressionNCT06365853Mirvetuximab SoravtansinePhase 2Locked · track to revealOngoingActive, not recruiting108 est.Feb 2027
A Study to Assess the Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-319 Moves Through the Bodies of Adult Participants With Relapsed or Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL), Follicular Lymphoma (FL), or Chronic Lymphocytic Leukemia (CLL)NCT05512390ABBV-319Phase 1Locked · track to revealOngoingActive, not recruiting39 est.Feb 2027
A Study to Assess the Adverse Events and How Intravenously Infused Livmoniplimab in Combination With Budigalimab Moves Through the Bodies of Adult Chinese Participants With Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC)NCT06487559LivmoniplimabPhase 1Locked · track to revealOngoingActive, not recruiting3 est.Feb 2027
A Study to Evaluate Sequential Administration of Injections of AGN-151586 Followed by BOTOX in Adult Participants for Treatment of Glabellar LinesNCT07756580AGN-151586Phase 1Locked · track to revealOngoingRecruiting120 est.Mar 2027
ConFeRStudy to Assess Prevalence of the Folate Receptor Alpha (FRa) in Adult Female Participants With Ovarian Cancer in Intercontinental (InterCon) CountriesNCT07539844Not yet scoredOngoingRecruiting1,000 est.Mar 2027
A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid TumorsNCT03893955ABBV-927Phase 1Locked · track to revealOngoingActive, not recruiting150 est.Mar 2027
OPTIMAL-3A Study to Assess the Use of Artificial Intellignce to Predict Eye Treatment Changes in Adult Participants With Diabetic Macular EdemaNCT07604545Not yet scoredStoppedWithdrawn0 est.Mar 2027
Study to Evaluate Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-291 Moves Through the Body in Adult Participants With Non-Hodgkin's LymphomaNCT06667687ABBV-291Phase 1Locked · track to revealOngoingActive, not recruiting21 est.Apr 2027
Ubro PedsStudy to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)NCT05125302UbrogepantPhase 3Locked · track to revealOngoingRecruiting1,059 est.May 2027
EMBARKA Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic DermatitisNCT06718101LutikizumabPhase 2Locked · track to revealOngoingActive, not recruiting83 est.May 2027
Study to Assess Participant Satisfaction After Jawline and Neck TreatmentNCT07794891OnabotulinumtoxinAPhase 4Not yet scoredOngoingNot yet recruiting100 est.Jun 2027
453 Ph1 CLLA Study Assessing Adverse Event and How Oral ABBV-453 Moves Through the Body in Adult Participants With Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)NCT06291220ObinutuzumabPhase 1Locked · track to revealOngoingActive, not recruiting4 est.Jul 2027
Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400NCT06084481ABBV-400Phase 1Locked · track to revealOngoingRecruiting325 est.Sept 2027
Study to Assess Real Life Effectiveness of Foslevodopa/Foscarbidopa in Adult German Participants at Initial Stages of Advanced Parkinson's Disease (EARLY-FOS)NCT06916507Not yet scoredOngoingRecruiting125 est.Sept 2027
UP-TAINEDA Study to Assess Disease Activity in Adolescent and Adult Participants With Atopic Dermatitis Who Receive Oral Upadacitinib Tablets in a Real-World SettingNCT05139836Locked · track to revealOngoingActive, not recruiting634 est.Sept 2027
P25-758 PUCCINReal-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson DiseaseNCT07227896Not yet scoredOngoingRecruiting100 est.Oct 2027
Study to Assess Adverse Events and Change in Disease Activity of Oral Venetoclax in Combination With Subcutaneous (SC) or Intravenous (IV) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Standard Induction Therapy in IndiaNCT07044687VenetoclaxPhase 4Locked · track to revealOngoingRecruiting100 est.Nov 2027
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II DisorderNCT06696755IcalcaprantPhase 2Locked · track to revealOngoingRecruiting195 est.Nov 2027
Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic AlterationsNCT06772623Telisotuzumab AdizutecanPhase 1Locked · track to revealOngoingRecruiting252 est.Nov 2027
UBRO MMStudy of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual MigraineNCT06417775UbrogepantPhase 3Locked · track to revealOngoingActive, not recruiting496 est.Nov 2027
CERVINOStudy Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple MyelomaNCT06158841EtentamigPhase 3Locked · track to revealOngoingActive, not recruiting421 est.Dec 2027
A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With SchizophreniaNCT07145918EmraclidinePhase 2Locked · track to revealOngoingRecruiting268 est.Feb 2028
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)NCT06568939Telisotuzumab VedotinPhase 2Locked · track to revealOngoingRecruiting150 est.Feb 2028
A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic MigraineNCT05711394AtogepantPhase 3Locked · track to revealOngoingRecruiting450 est.Mar 2028
Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related ComorbiditiesNCT07752979ABBV-295Phase 2Not yet scoredOngoingRecruiting360 est.Mar 2028
AndroMETa-CRCA Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal CancerNCT06820463Telisotuzumab AdizutecanPhase 2Locked · track to revealOngoingRecruiting390 est.Mar 2028
DREAMStudy to Assess Change in Quality of Life of Risankizumab Treatment in Adult Participants With Moderate-to-Severe Plaque PsoriasisNCT07039110Locked · track to revealOngoingRecruiting700 est.Mar 2028
Step-Up HSA Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF TherapyNCT05889182UpadacitinibPhase 3Locked · track to revealOngoingActive, not recruiting1,328 est.Mar 2028
A Study to Assess Adverse Events and How Intravenous (IV) Pivekimab Sunirine Moves Through the Body in Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)NCT07306832Pivekimab SunirinePhase 1Locked · track to revealOngoingRecruiting18 est.Apr 2028
NAAVIGATESurabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular EdemaNCT07592273Surabgene LomparvovecPhase 2Locked · track to revealOngoingRecruiting576 est.Jun 2028
Study to Assess Change in Disease Activity of Oral Venetoclax in Adult Participants With Recurring Relapsed or Refractory (R/R) Waldenström Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)NCT07387471VenetoclaxPhase 2Locked · track to revealOngoingActive, not recruiting14 est.Jul 2028
Study to Assess Adverse Events and How Effective NOA LIFT is Compared to JUVÉDERM VOLIFT With Lidocaine for the Correction of Nasolabial Folds in AdultsNCT07794878NOA LIFTPhase 3Not yet scoredOngoingRecruiting288 est.Aug 2028
Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia RepairNCT07226791AGN-151607-DPPhase 2Locked · track to revealOngoingRecruiting200 est.Sept 2028
A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With GlaucomaNCT06822738XEN63 Glaucoma Treatment SystemPhase 3Locked · track to revealOngoingRecruiting130 est.Nov 2028
A Study to Assess Adverse Events and Change in Disease Activity With Treatment Combinations With Telisotuzumab Adizutecan in Adults Participants With Pancreatobiliary CancersNCT07769502Telisotuzumab AdizutecanPhase 2Not yet scoredOngoingNot yet recruiting168 est.Nov 2028
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)NCT04928846Telisotuzumab VedotinPhase 3Locked · track to revealOngoingRecruiting768 est.Dec 2028
FLORENZAA Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian CancerNCT07059845Mirvetuximab SoravtansinePhase 2Locked · track to revealOngoingRecruiting400 est.Jan 2029
A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)NCT07607964ABBV-519Phase 1Locked · track to revealOngoingRecruiting30 est.Jan 2029
FORTIFYA Study of the Efficacy and Safety of Risankizumab in Participants With Crohn's DiseaseNCT03105102Risankizumab IVPhase 3Locked · track to revealOngoingActive, not recruiting1,336 est.Feb 2029
RISEA Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's DiseaseNCT05995353RisankizumabPhase 3Locked · track to revealOngoingRecruiting110 est.Apr 2029
SEZanneA Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung CancerNCT07155174ABBV-706Phase 2Locked · track to revealOngoingRecruiting180 est.Apr 2029
A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous TumorsNCT07241039ABBV-711Phase 1Locked · track to revealOngoingRecruiting220 est.Apr 2029
View all trials2,088

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We check every one of its trials daily and tell you what moved.

  • Status changeStatus moved to completedWas recruiting · always alerts
  • Completion date movePrimary completion slipped 210 daysSlips and pull-ins of 30+ days
  • New trialNew trial registered in your scopeFirst posted within 30 days
  • Enrollment changeEnrollment grew to 1,200Moves of 15%+ or count finalised
  • Substantive record editPrimary endpoint redefined from 24 to 52 weeksRead overnight and flagged in plain English
US registryClinicalTrials.gov
EU registryCTIS · Soon
2,088

Trials as lead sponsor

117

Recruiting now

599

Phase 3 trials

457

Phase 2 trials

477

Phase 1 trials

167

Phase 4 trials