Immunology & inflammation · Live ClinicalTrials.gov data

Dupilumab (Dupixent) clinical trial pipeline

The timeline below tracks the 16 largest phase 2–4 dupilumab (Dupixent) trials on ClinicalTrials.gov by enrolment, 4 of them actively recruiting. The next phase 3 primary completion among them is expected Jun 2027. Refreshed daily. Add up to four competitors to compare pipelines side by side.

16+

Major trials tracked

7

Phase 3 trials

4

Actively recruiting

Jun 2027

Next phase 3 primary completion

7,668

Participants across trials

Sanofi

Lead sponsor by trial count

dupilumab (16)8 active2014–2030
dupilumab
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingNot yet recruitingCompletedTerminated
'14
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'18
'20
'22
'24
'26
'28
'30
dupilumab
Study of Dupilumab and Immune Responses in Adults With Atopic Dermatitis (AD)P2
SOLO 2P3
SOLO-CONTINUEP3
Evaluation of Dupilumab in Patients With Persistent Asthma (Liberty Asthma Quest)P3
Study to Investigate the Efficacy and Safety of Dupilumab Administered With Topical Corticosteroids (TCS) in Participants ≥6 to <12 Years With Severe Atopic Dermatitis (AD)P3
Study of Dupilumab for the Treatment of Patients With Prurigo Nodularis, Inadequately Controlled on Topical Prescription Therapies or When Those Therapies Are Not Advisable (LIBERTY-PN PRIME)P3
Study of Dupilumab for the Treatment of Patients With Prurigo Nodularis, Inadequately Controlled on Topical Prescription Therapies or When Those Therapies Are Not Advisable (PRIME2)P3
LIBERTY-BPP2
GENESISP2
ATLASP4
Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)P3
DUPLEX-ADP2
AEOLUSP4
WIDUSAP4
A Study to Evaluate Efficacy and Safety of IBI356 in Participants With Moderate to Severe Atopic DermatitisP2
MISSIONP4

Upcoming readouts

6 ahead · dupilumab

Select a trial to load its full ClinicalTrials.gov record.

Key dupilumab trials

Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.

TrialTitlePhaseStatusPrimary completion
NCT06818019WIDUSA: Withdrawal of Dupilumab in Severe AsthmaPhase 4RecruitingDec 2027
NCT07053423AEOLUS: A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥4…Phase 4RecruitingDec 2028
NCT05097287ATLAS: Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adul…Phase 4Active, not recruitingMar 2027
NCT07587658MISSION: This After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is Better Than …Phase 4Not yet recruitingJul 2028
NCT05263206Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chron…Phase 3RecruitingJun 2027
NCT02277769SOLO 2: Study of Dupilumab (REGN668/SAR231893) Monotherapy Administered to Adult Patients With Moderate-…Phase 3CompletedOct 2015
NCT02395133SOLO-CONTINUE: A Study to Confirm the Efficacy and Safety of Different Dupilumab Dose Regimens in Adults With A…Phase 3CompletedJul 2016
NCT02414854Evaluation of Dupilumab in Patients With Persistent Asthma (Liberty Asthma Quest)Phase 3CompletedJul 2017
NCT03345914Study to Investigate the Efficacy and Safety of Dupilumab Administered With Topical Corticostero…Phase 3CompletedJun 2019
NCT04202679Study of Dupilumab for the Treatment of Patients With Prurigo Nodularis, Inadequately Controlled…Phase 3CompletedAug 2021
NCT04183335Study of Dupilumab for the Treatment of Patients With Prurigo Nodularis, Inadequately Controlled…Phase 3CompletedNov 2021
NCT07330934A Study to Evaluate Efficacy and Safety of IBI356 in Participants With Moderate to Severe Atopic…Phase 2RecruitingJun 2027

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FAQ

How many clinical trials are running for dupilumab?
ClinicalTrials.gov lists more than 16 phase 2–4 dupilumab trials. This page tracks the 16 largest by enrolment: 5 phase 2, 7 phase 3, and 4 phase 4 among them, with 4 actively recruiting. Updated daily.
Are there clinical trials for Dupixent?
Dupixent is the brand name for dupilumab, so dupilumab trials on ClinicalTrials.gov cover it. ClinicalTrials.gov lists more than 16 phase 2–4 dupilumab trials. This page tracks the 16 largest by enrolment: 5 phase 2, 7 phase 3, and 4 phase 4 among them, with 4 actively recruiting. Updated daily.
Where does this data come from?
All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare dupilumab against other drugs?
Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.

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