16+
Major trials tracked
Immunology & inflammation · Live ClinicalTrials.gov data
Dupilumab (Dupixent) clinical trial pipeline
The timeline below tracks the 16 largest phase 2–4 dupilumab trials on ClinicalTrials.gov by enrolment, 3 of them actively recruiting. The next phase 3 primary completion among them is expected Apr 2027. Refreshed daily — add up to four competitors to compare pipelines side by side.
4
Phase 3 trials
3
Actively recruiting
Apr 2027
Next phase 3 primary completion
4,433
Participants across trials
Sanofi
Lead sponsor by trial count
dupilumab (16)9 active2012–2030
dupilumab
'12
'14
'16
'18
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'22
'24
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'28
'30
dupilumab
Study of Dupilumab in Adult Patients With Extrinsic Moderate-to-Severe Atopic DermatitisP2
An Evaluation of Dupilumab in Patients With Moderate to Severe Uncontrolled AsthmaP2
Efficacy and Safety of Dupilumab in Participants ≥12 to <18 Years of Age, With Moderate-to-severe Atopic DermatitisP3
Effect of Dupilumab (Anti-IL4Rα) on the Host-Microbe Interface in Atopic DermatitisP4
LIBERTY-BPP2
Dupilumab for the Treatment of Chronic Inducible Cold Urticaria in Patients Who Remain Symptomatic Despite the Use of H1-antihistamine (LIBERTY-CINDU CUrIADS)P3
GENESISP2
ATLASP4
VIAP4
LEADSP4
Study of Eblasakimab in Male or Female Moderate-to-Severe Atopic Dermatitis Patients Previously Treated With DupilumabP2
DISCOVERP4
A Study Assessing Esophageal Function and Remodeling With Dupilumab Compared With Placebo for 24 Weeks Followed by 104 Weeks Open Label in Adult Participants With EoE (REMOdeling With Dupilumab in Eosinophilic Esophagitis Long-term Trial)P4
Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)P3
PEDALP2
A Phase III Study of GS101 Injection to Dupixent®P3
Upcoming readouts
4 ahead · dupilumab
Select a trial to load its full ClinicalTrials.gov record.
Key dupilumab trials
Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Each links to its full ClinicalTrials.gov record.
| Trial | Title | Phase | Status | Primary completion |
|---|---|---|---|---|
| NCT04380038 | VIA — Viral Infection in Asthma (VIA) Study | Phase 4 | Recruiting | Jun 2026 |
| NCT06101095 | A Study Assessing Esophageal Function and Remodeling With Dupilumab Compared With Placebo for 24 Weeks Followe… | Phase 4 | Active, not recruiting | Nov 2025 |
| NCT05097287 | ATLAS — Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients Wit… | Phase 4 | Active, not recruiting | Mar 2027 |
| NCT05590585 | DISCOVER — Dupilumab in Adolescent and Adult Skin of Color Participants: Open-label Moderate-to-severe Eczema Trial | Phase 4 | Completed | Nov 2024 |
| NCT05436535 | LEADS — Longitudinal Endotyping Of Atopic Dermatitis Through Transcriptomic Skin Analysis | Phase 4 | Completed | Apr 2025 |
| NCT03389893 | Effect of Dupilumab (Anti-IL4Rα) on the Host-Microbe Interface in Atopic Dermatitis | Phase 4 | Terminated | Apr 2020 |
| NCT06191315 | Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years … | Phase 3 | Recruiting | Dec 2028 |
| NCT07386743 | A Phase III Study of GS101 Injection to Dupixent® | Phase 3 | Not yet recruiting | Apr 2027 |
| NCT03054428 | Efficacy and Safety of Dupilumab in Participants ≥12 to <18 Years of Age, With Moderate-to-severe Atopic Derma… | Phase 3 | Completed | Apr 2018 |
| NCT04681729 | Dupilumab for the Treatment of Chronic Inducible Cold Urticaria in Patients Who Remain Symptomatic Despite the… | Phase 3 | Completed | Feb 2023 |
| NCT05866562 | PEDAL — Dupilumab in the Treatment of Pediatric Alopecia Areata | Phase 2 | Recruiting | Aug 2028 |
| NCT01548404 | Study of Dupilumab in Adult Patients With Extrinsic Moderate-to-Severe Atopic Dermatitis | Phase 2 | Completed | Mar 2013 |
Related drug pipelines
FAQ
- How many clinical trials are running for dupilumab?
- ClinicalTrials.gov lists more than 16 phase 2–4 dupilumab trials. This page tracks the 16 largest by enrolment: 6 phase 2, 4 phase 3, and 6 phase 4 among them, with 3 actively recruiting. Updated daily.
- Where does this data come from?
- All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
- Can I compare dupilumab against other drugs?
- Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
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