Immunology & inflammation · Live ClinicalTrials.gov data

Lebrikizumab (Ebglyss) clinical trial pipeline

The timeline below tracks the 16 largest phase 2–4 lebrikizumab trials on ClinicalTrials.gov by enrolment, 2 of them actively recruiting. The next phase 3 primary completion among them is expected Sept 2026. Refreshed daily — add up to four competitors to compare pipelines side by side.

16+

Major trials tracked

14

Phase 3 trials

2

Actively recruiting

Sept 2026

Next phase 3 primary completion

8,433

Participants across trials

Eli Lilly and Company

Lead sponsor by trial count

lebrikizumab (16)7 active20132029
lebrikizumab
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingEnrolling by invitationCompletedTerminated
'13
'15
'17
'19
'21
'23
'25
'27
'29
lebrikizumab
A Study of Lebrikizumab in Participants With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller MedicationP3
A Study of Lebrikizumab in Participants With Uncontrolled Asthma on Inhaled Corticosteroids and a Second Controller MedicationP3
A Study of Lebrikizumab in Adolescent Participants With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller MedicationP3
A Study of Lebrikizumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)P2
A Study Evaluating the Efficacy and Safety of Lebrikizumab in Adult Patients With Mild to Moderate AsthmaP3
A Study to Evaluate Safety and Efficacy of Lebrikizumab in Participants With Chronic Obstructive Pulmonary Disease (COPD)P2
Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis (ADvocate1)P3
ADvocate2P3
ADjoinP3
ADvantageP3
ADorable-1P3
ADorable-2P3
A Study of Lebrikizumab (LY3650150) With/Without Topical Corticosteroid Treatment in Participants With Moderate-to-Severe Atopic DermatitisP3
A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis (PREPARED-1)P3
A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)P3
ADhope 2P3

Upcoming readouts

4 ahead · lebrikizumab

Select a trial to load its full ClinicalTrials.gov record.

Key lebrikizumab trials

Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Each links to its full ClinicalTrials.gov record.

TrialTitlePhaseStatusPrimary completion
NCT06339008A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis (PREPARED-1)Phase 3RecruitingSept 2026
NCT06338995A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With …Phase 3RecruitingMay 2027
NCT06280716A Study of Lebrikizumab (LY3650150) With/Without Topical Corticosteroid Treatment in Participants With Moderat…Phase 3Active, not recruitingSept 2025
NCT05559359ADorable-1 — A Study of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopi…Phase 3Active, not recruitingJan 2026
NCT06526182ADhope 2 — A Study of Lebrikizumab Treatment in Adults and Adolescents With Moderate-to-Severe Atopic DermatitisPhase 3Active, not recruitingApr 2027
NCT05735483ADorable-2 — A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <1…Phase 3Enrolling by invitationDec 2027
NCT02104674A Study Evaluating the Efficacy and Safety of Lebrikizumab in Adult Patients With Mild to Moderate AsthmaPhase 3CompletedMay 2016
NCT01867125A Study of Lebrikizumab in Participants With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Seco…Phase 3CompletedJan 2017
NCT01868061A Study of Lebrikizumab in Participants With Uncontrolled Asthma on Inhaled Corticosteroids and a Second Contr…Phase 3CompletedJan 2017
NCT04146363Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis (ADv…Phase 3CompletedJun 2021
NCT04178967ADvocate2 — Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic DermatitisPhase 3CompletedJul 2021
NCT05149313ADvantage — A Study of Lebrikizumab in Combination With Topical Corticosteroids in Patients With Atopic Dermatitis (AD) Th…Phase 3CompletedJan 2023

FAQ

How many clinical trials are running for lebrikizumab?
ClinicalTrials.gov lists more than 16 phase 2–4 lebrikizumab trials. This page tracks the 16 largest by enrolment: 2 phase 2, 14 phase 3, and 0 phase 4 among them, with 2 actively recruiting. Updated daily.
Where does this data come from?
All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare lebrikizumab against other drugs?
Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
Join the waitlist

Be the first to access ComplyRx

We'll let you know as soon as your spot opens to use ComplyRx.

By joining, you agree to our Privacy Policy.