Immunology & inflammation · Live ClinicalTrials.gov data

Risankizumab (Skyrizi) clinical trial pipeline

The timeline below tracks the 16 largest phase 2–4 risankizumab (Skyrizi) trials on ClinicalTrials.gov by enrolment, 2 of them actively recruiting. The next phase 3 primary completion among them is expected Jan 2027. Refreshed daily. Add up to four competitors to compare pipelines side by side.

16+

Major trials tracked

10

Phase 3 trials

2

Actively recruiting

Jan 2027

Next phase 3 primary completion

8,433

Participants across trials

AbbVie

Lead sponsor by trial count

risankizumab (16)7 active2016–2030
risankizumab
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingNot yet recruitingCompletedUnknown status
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risankizumab
BI 655066 (Risankizumab) Compared to Placebo and Active Comparator (Ustekinumab) in Patients With Moderate to Severe Chronic Plaque PsoriasisP3
BI 655066 / ABBV-066 (Risankizumab) in Moderate to Severe Plaque Psoriasis With Randomized Withdrawal and Re-treatmentP3
BI 655066/ABBV-066 (Risankizumab) Compared to Active Comparator (Adalimumab) in Patients With Moderate to Severe Chronic Plaque PsoriasisP3
A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Crohn's Disease Who Failed Prior Biologic TreatmentP3
A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative ColitisP2
COMMANDP3
DETERMINED 1P2
A Study of the Safety and Efficacy of Risankizumab in Adult Participants With Plaque Psoriasis Who Have Had a Suboptimal Response to Secukinumab or IxekizumabP3
PSORIASI_RISAP4
Study of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Change in Disease Activity And Adverse Events in Adult Participants With Moderate Plaque Psoriasis Who Are Candidates for Systemic TherapyP4
SOPRANO-CDP4
UnlIMMitedP4
AFFIRMP3
IZAR-2P3
Risankizumab for Fibrostenotic Crohn's Disease TreatmentP3
CHARGEP3

Upcoming readouts

6 ahead · risankizumab

Select a trial to load its full ClinicalTrials.gov record.

Key risankizumab trials

Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.

TrialTitlePhaseStatusPrimary completion
NCT05169593SOPRANO-CD: Prevention of Postoperative Endoscopic Recurrence With Endoscopy-driven Versus Systematic Biolog…Phase 4RecruitingOct 2027
NCT04908475Study of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Chang…Phase 4CompletedApr 2023
NCT05969223UnlIMMited: Study to Assess the Safety and Efficacy of Subcutaneously Injected Risankizumab in Adult Partici…Phase 4CompletedJan 2025
NCT04722640PSORIASI_RISA: Exploring the Effects of IL-23 Inhibition by Risankizumab on Psoriasis AutoimmunityPhase 4UnknownJan 2022
NCT07499232CHARGE: A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Cro…Phase 3RecruitingNov 2028
NCT06641089IZAR-2: Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate R…Phase 3Active, not recruitingJan 2027
NCT06063967AFFIRM: A Study to Assess Adverse Events and Change in Disease Activity of Risankizumab Subcutaneous Ind…Phase 3Active, not recruitingMar 2027
NCT07177118Risankizumab for Fibrostenotic Crohn's Disease TreatmentPhase 3Not yet recruitingJun 2028
NCT03398135COMMAND: A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Coliti…Phase 3Active, not recruitingSept 2028
NCT02684370BI 655066 (Risankizumab) Compared to Placebo and Active Comparator (Ustekinumab) in Patients Wit…Phase 3CompletedDec 2016
NCT02694523BI 655066/ABBV-066 (Risankizumab) Compared to Active Comparator (Adalimumab) in Patients With Mo…Phase 3CompletedAug 2017
NCT02672852BI 655066 / ABBV-066 (Risankizumab) in Moderate to Severe Plaque Psoriasis With Randomized Withd…Phase 3CompletedAug 2017

Track risankizumab with ComplyRx

Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.

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FAQ

How many clinical trials are running for risankizumab?
ClinicalTrials.gov lists more than 16 phase 2–4 risankizumab trials. This page tracks the 16 largest by enrolment: 2 phase 2, 10 phase 3, and 4 phase 4 among them, with 2 actively recruiting. Updated daily.
Are there clinical trials for Skyrizi?
Skyrizi is the brand name for risankizumab, so risankizumab trials on ClinicalTrials.gov cover it. ClinicalTrials.gov lists more than 16 phase 2–4 risankizumab trials. This page tracks the 16 largest by enrolment: 2 phase 2, 10 phase 3, and 4 phase 4 among them, with 2 actively recruiting. Updated daily.
Where does this data come from?
All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare risankizumab against other drugs?
Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.

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