Immunology & inflammation · Live ClinicalTrials.gov data

Deucravacitinib (Sotyktu) clinical trial pipeline

The timeline below tracks the 16 largest phase 2–4 deucravacitinib (Sotyktu) trials on ClinicalTrials.gov by enrolment, 2 of them actively recruiting. The next phase 3 primary completion among them is expected Oct 2026. Refreshed daily. Add up to four competitors to compare pipelines side by side.

16+

Major trials tracked

7

Phase 3 trials

2

Actively recruiting

Oct 2026

Next phase 3 primary completion

7,484

Participants across trials

Bristol-Myers Squibb

Lead sponsor by trial count

deucravacitinib (16)13 active2017–2032
deucravacitinib
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingNot yet recruitingCompletedTerminated
'17
'19
'21
'23
'25
'27
'29
'31
deucravacitinib
An Investigational Study to Evaluate BMS-986165 in Participants With Systemic Lupus ErythematosusP2
An Investigational Study of Experimental Medication BMS-986165 in Participants With Moderate to Severe Crohn's DiseaseP2
Long-Term Safety and Efficacy Study of Deucravacitinib in Participants With Systemic Lupus ErythematosusP2
Safety and Efficacy of Deucravacitinib in Participants With Moderate to Severe Ulcerative ColitisP2
A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)P2
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic DrugsP3
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor TreatmentP3
A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Alopecia AreataP2
POETYK SLE-1P3
POETYK SLE-2P3
A Study to Evaluate Effectiveness and Safety of Deucravacitinib in Participants With Non-Pustular Palmoplantar and Genital PsoriasisP4
A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis (ICONIC-ADVANCE 2)P3
ViTYKP2
A Clinical Study to Evaluate the Efficacy and Safety of D-2570 in the Treatment of Moderate to Severe Plaque PsoriasisP3
COMBoP4
Continued Access to Deucravacitinib for Adult SLE/SjD and Pediatric PsO/PsA Study CompletersP3

Upcoming readouts

6 ahead · deucravacitinib

Select a trial to load its full ClinicalTrials.gov record.

Key deucravacitinib trials

Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.

TrialTitlePhaseStatusPrimary completion
NCT07280702COMBo: Deucravacitinib-TNFi Combination Therapy for Difficult-to-Control Psoriatic DiseasePhase 4RecruitingDec 2027
NCT06042920A Study to Evaluate Effectiveness and Safety of Deucravacitinib in Participants With Non-Pustula…Phase 4TerminatedApr 2025
NCT07326813A Clinical Study to Evaluate the Efficacy and Safety of D-2570 in the Treatment of Moderate to S…Phase 3RecruitingJul 2027
NCT04908202A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Partici…Phase 3Active, not recruitingSept 2024
NCT04908189A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Partici…Phase 3Active, not recruitingNov 2024
NCT06220604A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psorias…Phase 3Active, not recruitingNov 2024
NCT05617677POETYK SLE-1: A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participa…Phase 3Active, not recruitingOct 2026
NCT05620407POETYK SLE-2: A Study to Evaluate Effectiveness and Safety of Deucravacitinib (BMS-986165) Compared With Place…Phase 3Active, not recruitingOct 2026
NCT07791199Continued Access to Deucravacitinib for Adult SLE/SjD and Pediatric PsO/PsA Study CompletersPhase 3Not yet recruitingOct 2030
NCT04857034A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid a…Phase 2Active, not recruitingAug 2024
NCT06327321ViTYK: Vitiligo Treatment by Targeting TYK2 Mediated ResponsesPhase 2Active, not recruitingNov 2026
NCT03934216Safety and Efficacy of Deucravacitinib in Participants With Moderate to Severe Ulcerative Coliti…Phase 2CompletedJun 2021

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Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.

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FAQ

How many clinical trials are running for deucravacitinib?
ClinicalTrials.gov lists more than 16 phase 2–4 deucravacitinib trials. This page tracks the 16 largest by enrolment: 7 phase 2, 7 phase 3, and 2 phase 4 among them, with 2 actively recruiting. Updated daily.
Are there clinical trials for Sotyktu?
Sotyktu is the brand name for deucravacitinib, so deucravacitinib trials on ClinicalTrials.gov cover it. ClinicalTrials.gov lists more than 16 phase 2–4 deucravacitinib trials. This page tracks the 16 largest by enrolment: 7 phase 2, 7 phase 3, and 2 phase 4 among them, with 2 actively recruiting. Updated daily.
Where does this data come from?
All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare deucravacitinib against other drugs?
Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.

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