Big pharma · BMY · 2,164 trials led

Bristol Myers Squibb clinical trial pipeline

2,164 trials as lead sponsor, 129 recruiting now, 396 in phase 3. Live from ClinicalTrials.gov, updated daily.

  • Status changeStatus moved to completedWas recruiting · always alerts
  • Completion date movePrimary completion slipped 210 daysSlips and pull-ins of 30+ days
  • New trialNew trial registered in your scopeFirst posted within 30 days
  • Enrollment changeEnrollment grew to 1,200Moves of 15%+ or count finalised
  • Substantive record editPrimary endpoint redefined from 24 to 52 weeksRead overnight and flagged in plain English
View trials

Archive historyJan 2023 to Sept 2026

98 recorded changes across Bristol Myers Squibb trials

Every status move, completion date shift and enrollment change ComplyRx has recorded across 40 of these trials. One is shown below.

Status changeStatus moved to recruiting from not yet recruitingNCT07686263 · recorded 14 Sept 2026
Track to read them

+94 more recorded changes · Track a drug to see every change the night it lands

Track nivolumab

Most active programmes

The drugs appearing most often across Bristol Myers Squibb's recently active trials. Comparator arms are excluded.

  • KarXT14 trials
  • Pumitamig13 trials
  • Nivolumab10 trials
  • Pemetrexed9 trials
  • Carboplatin9 trials
  • Adagrasib8 trials

Upcoming readouts

Next primary completion dates among Bristol Myers Squibb's active phase 2 and phase 3 trials. Dates are registry estimates and move often, which is exactly what the tracker watches.

Top therapeutic areas

Conditions studied most often across Bristol Myers Squibb's recently active trials.

  • Schizophrenia7 trials
  • Alzheimer Disease4 trials
  • Alzheimer's Disease4 trials
  • Melanoma3 trials
  • Plaque Psoriasis3 trials
  • Agitation2 trials

Bristol Myers Squibb pipeline by phase

The main study drugs across 218 active trials Bristol Myers Squibb leads on ClinicalTrials.gov. Each drug sits in the highest phase among its currently active trials, which can be lower than a phase it has already completed.

Phase 319 drugs

Bristol Myers Squibb phase 3 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
Nivolumab102Sept 2026 est.NCT06561386 · NCT04099251 · NCT04025879
AdagrasibMRTX84984Oct 2026 est.NCT06875310 · NCT04793958 · NCT04685135
Pumitamig77Sept 2028 est.NCT07361510 · NCT07361497 · NCT07680764
GolcadomideBMS-986369 · CC-9928261Dec 2026 est.NCT06911502 · NCT06356129 · NCT06425302
BMS-986353CC-975405Jul 2027 est.NCT07335562 · NCT07603557 · NCT07015983
Iza-brenBMS-98650754Mar 2028 est.NCT07680790 · NCT07106762 · NCT07100080
Repotrectinib53Sept 2026 est.NCT06140836 · NCT04094610 · NCT03093116
MezigdomideCC-9248042Oct 2026 est.NCT05552976 · NCT05519085 · NCT05372354
Arlocabtagene AutoleucelBMS-98639333Dec 2027 est.NCT06615479 · NCT06297226 · NCT06121843
BMS-9862783Oct 2026 est.NCT07441408 · NCT06025578 · NCT06003426
IberdomideCC-2203Dec 2028 est.NCT05827016 · NCT04884035 · NCT02773030
RYZ10131Dec 2026 est.NCT05477576 · NCT06590857 · NCT05595460
Abatacept1NCT04909801
Belatacept11Dec 2032 est.NCT04877288
BMS-9863651Sept 2027 est.NCT06764485
BMS-986489 (Atigotatug+Nivolumab)11Apr 2028 est.NCT06646276
idecabtagene vicleucel1NCT06045806
Ipilimumab1NCT04008030
Nivolumab and rHuPH201NCT04810078

Phase 212 drugs

Bristol Myers Squibb phase 2 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
NavlimetostatBMS-986504 · MRTX1719107Dec 2026 est.NCT07492680 · NCT07076121 · NCT07063745
BMS-98636832Feb 2027 est.NCT06808984 · NCT06782490 · NCT07700329
BMS-98643532Dec 2026 est.NCT06122779 · NCT07248839 · NCT07226817
Oral AzacitidineCC-4863Jul 2028 est.NCT05469737 · NCT05413018 · NCT05197426
BMS-9864462Mar 2027 est.NCT06268886 · NCT07780383
Fludarabine21Mar 2029 est.NCT04245839 · NCT07115745
Adagrasib oral dose of 400 mg twice daily tablets1Sept 2026 est.NCT05609578
BMS-9865111Nov 2028 est.NCT07772531
Gene-modified (GM) T cell therapy11Nov 2036 est.NCT03435796
Relatlimab1NCT03470922
relatlimab+nivolumab1NCT06101134
Rituximab11Jan 2028 est.NCT07015242

Phase 134 drugs

Bristol Myers Squibb phase 1 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
AG-1201NCT02677922
BMS-98552111Nov 2026 est.NCT07283263
BMS-9861581Aug 2028 est.NCT04817007
BMS-98634011Aug 2031 est.NCT04895709
BMS-9864491Sept 2026 est.NCT05888831
BMS-98645311May 2030 est.NCT06153251
BMS-98645411Jun 2027 est.NCT07171983
BMS-98645811Oct 2027 est.NCT06090539
BMS-98646011Aug 2029 est.NCT06067841
BMS-98646311Dec 2028 est.NCT06476808

Phase 46 drugs

Bristol Myers Squibb phase 4 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
DeucravacitinibBMS-9861652211Oct 2026 est.NCT06875960 · NCT07791199 · NCT07116967
Xanomeline/Trospium Chloride1715Nov 2026 est.NCT07221877 · NCT07288567 · NCT07285798
Mavacamten128Nov 2026 est.NCT07004972 · NCT06112743 · NCT06253221
LuspaterceptACE-536102Jul 2027 est.NCT05891249 · NCT06045689 · NCT05949684
OzanimodBMS-98637443Dec 2028 est.NCT06396039 · NCT06408259 · NCT05076175
Nivolumab + Relatlimab2May 2029 est.NCT07459543 · NCT05625399

Combination backbones Dexamethasone (1 trial). Established agents these trials combine with, listed separately from the drugs under study.

Derived from 218 active trials Bristol Myers Squibb leads; 213 name an intervention, folding into 71 phased drugs. 11 interventions carry no registry phase (observational studies, tests and devices) and are not shown. This is ComplyRx's reading of the registry, not Bristol Myers Squibb's own pipeline disclosure.

Bristol Myers Squibb trials

The 50 most significant of Bristol Myers Squibb's recently active trials, soonest estimated readout first.
Select any row for the full record; the change timeline unlocks with tracking.

TrialPhaseStabilityStatusEnrollmentEst. readout
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 AlterationsNCT04094610Oral repotrectinib (TPX-0005)Phase 1Locked · track to revealOngoingRecruiting75 est.30 Sept 2026
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)NCT05511363KarXTPhase 3Locked · track to revealOngoingRecruiting410 est.5 Oct 2026
Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)NCT05853575AdagrasibPhase 2Locked · track to revealOngoingActive, not recruiting200 est.30 Oct 2026
BALSAM-1A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I DisorderNCT06951698KarXTPhase 3Locked · track to revealOngoingRecruiting274 est.1 Nov 2026
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)NCT06951711KarXTPhase 3Locked · track to revealOngoingRecruiting274 est.2 Nov 2026
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)NCT06585787KarXTPhase 3Locked · track to revealOngoingRecruiting406 est.24 Nov 2026
A Study to Evaluate the Metabolism, the Routes and Extent of Elimination, and Drug Levels of [14C]Navlimetostat (BMS-986504) in Healthy Female ParticipantsNCT07777133NavlimetostatPhase 1Not yet scoredOngoingNot yet recruiting6 est.5 Dec 2026
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)NCT06126224KarXTPhase 3Locked · track to revealOngoingRecruiting500 est.9 Dec 2026
A Study to Evaluate the Pharmacokinetics and Safety of Golcadomide in Participants With Severe Renal Impairment and End-Stage Renal Disease Compared With Participants With Normal Renal FunctionNCT07763418GolcadomidePhase 1Not yet scoredOngoingNot yet recruiting30 est.14 Dec 2026
A Study to Assess the Relative Bioavailability of BMS-986435 and Food Effect on the BMS-986435 in Healthy Adult ParticipantsNCT07226817BMS-986435Phase 1Locked · track to revealOngoingRecruiting240 est.17 Dec 2026
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell DiseaseNCT06481306BMS-986470Phase 1Locked · track to revealOngoingRecruiting224 est.6 Jan 2027
SUCCESSOR-1A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)NCT05519085mezigdomidePhase 3Locked · track to revealOngoingRecruiting810 est.10 Jan 2027
Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.NCT07165132RYZ401Phase 1Locked · track to revealOngoingRecruiting104 est.Feb 2027
A Study of Navlimetostat (BMS-986504) Drug Interactions and Food Effect in Healthy ParticipantsNCT07800897NavlimetostatPhase 1Locked · track to revealOngoingNot yet recruiting80 est.25 Mar 2027
A Study to Evaluate Novel KarX and KarT Prototypes Versus the KarXT and KarX-EC Reference Following Single Doses, Explore the Effect of Food After Multiple Doses of Selected Prototypes, and Evaluate Alternative Formulations of KarX and KarXT Following Single and Multiple Ascending DosesNCT07063342Xanomeline/Trospium Chloride CapsulePhase 1Locked · track to revealOngoingRecruiting236 est.29 Mar 2027
MSSA Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis SpasticityNCT06782490BMS-986368Phase 2Locked · track to revealOngoingRecruiting200 est.26 May 2027
A Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety and Preliminary Efficacy of Mezigdomide in Combination With Elranatamab in Participants With Relapsed and/or Refractory Multiple MyelomaNCT06988488ElranatamabPhase 1Locked · track to revealOngoingRecruiting62 est.31 May 2027
A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participants With Early Alzheimer's Disease After Multiple Dose AdministrationNCT07780383BMS-986446Phase 1Not yet scoredOngoingNot yet recruiting84 est.17 Jun 2027
A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXTNCT07061288KarXTPhase 1Locked · track to revealOngoingRecruiting131 est.21 Jun 2027
A Study to Determine the Efficacy and Safety of Luspatercept in Adult Participants and to Evaluate the Safety and Pharmacokinetics in and Adolescent Participants With Alpha (α)-ThalassemiaNCT05664737LuspaterceptPhase 2Locked · track to revealOngoingActive, not recruiting189 est.16 Jul 2027
rechARgeA Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate CancerNCT06764485BMS-986365Phase 3Locked · track to revealOngoingActive, not recruiting960 est.12 Sept 2027
Long-Term Real-World Safety of Cobenfy in Adults With SchizophreniaNCT07783373xanomeline-trospium chlorideLocked · track to revealOngoingActive, not recruiting3,000 est.26 Sept 2027
A Study to Assess BMS-986458 Alone and in Combination With Anti-lymphoma Agents in Relapsed/Refractory Non-Hodgkin LymphomasNCT06090539BMS-986458Phase 1Locked · track to revealOngoingRecruiting460 est.28 Oct 2027
Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's DiseaseNCT06808984BMS-986368Phase 2Locked · track to revealOngoingRecruiting120 est.26 Nov 2027
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP DeletionNCT05245500MRTX1719Phase 1Locked · track to revealOngoingRecruiting336 est.10 Dec 2027
A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)NCT06615479BMS-986393Phase 3Locked · track to revealOngoingRecruiting440 est.30 Dec 2027
A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System LymphomaNCT07015242RituximabPhase 2Locked · track to revealOngoingRecruiting65 est.9 Jan 2028
A Study to Continue the Administration of Deucravacitinib in Participants With Systemic Lupus Erythematosus (SLE) or Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE) Who Have Completed Study IM011074 or Study IM011132NCT06875960BMS-986165Phase 4Locked · track to revealOngoingRecruiting35 est.31 Jan 2028
A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib StudiesNCT07415031AdagrasibPhase 2Locked · track to revealOngoingRecruiting170 est.16 Feb 2028
BENCHMARK-SLEA Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 ImmunosuppressantsNCT07175285Current standard of care treatment optionsNot yet scoredOngoingRecruiting223 est.24 Mar 2028
A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).NCT06646276BMS-986489 (Atigotatug+Nivolumab)Phase 3Locked · track to revealOngoingRecruiting530 est.6 Apr 2028
A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)NCT06929273KarXTPhase 3Locked · track to revealOngoingRecruiting450 est.13 Jun 2028
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)NCT07379827Xanomeline and trospium chloride (KarXT)Locked · track to revealOngoingRecruiting1,500 est.20 Jun 2028
A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid TumorsNCT07160725BMS-986517Phase 1Locked · track to revealOngoingRecruiting540 est.31 Jul 2028
A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)NCT07492680BMS-986504Phase 2Locked · track to revealOngoingRecruiting260 est.15 Aug 2028
MINDSET 1A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's DiseaseNCT06976216KarXTPhase 3Locked · track to revealOngoingRecruiting586 est.11 Sept 2028
MINDSET 2A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)NCT06976203KarXTPhase 3Locked · track to revealOngoingRecruiting586 est.11 Sept 2028
A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)NCT07680764PumitamigPhase 2Not yet scoredOngoingRecruiting160 est.15 Sept 2028
TRACY-1Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.NCT06590857RYZ101Phase 1Locked · track to revealOngoingActive, not recruiting16 est.Oct 2028
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7NCT04613596AdagrasibPhase 2Locked · track to revealOngoingRecruiting626 est.31 Oct 2028
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's DiseaseNCT07011745Xanomeline/Trospium Chloride CapsulePhase 3Locked · track to revealOngoingRecruiting426 est.3 Nov 2028
A Study to Evaluate BMS-986511 in Adults With Major Depressive DisorderNCT07772531BMS-986511Phase 2Not yet scoredOngoingNot yet recruiting200 est.6 Nov 2028
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)NCT07011732Xanomeline/Trospium Chloride CapsulePhase 3Locked · track to revealOngoingRecruiting426 est.24 Nov 2028
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)NCT07100080Iza-brenPhase 2Locked · track to revealOngoingRecruiting500 est.15 Dec 2028
A Study to Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in IndiaNCT05891249LuspaterceptPhase 4Locked · track to revealOngoingActive, not recruiting85 est.16 Dec 2028
A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque PsoriasisNCT04772079DeucravacitinibPhase 3Locked · track to revealOngoingRecruiting153 est.1 Jan 2029
Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)NCT07101094xanomeline and trospium chloride (X/T) therapyLocked · track to revealOngoingRecruiting300 est.31 Jan 2029
Relapse Prevention Trial Evaluating KarXT Treatment in SchizophreniaNCT07686263Xanomeline/Trospium ChloridePhase 3Locked · track to revealOngoingRecruiting472 est.3 Mar 2029
A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination Therapy in Participants With Relapsed/Refractory Small Cell Lung CancerNCT07325136BMS-986525Phase 1Locked · track to revealOngoingRecruiting240 est.23 Apr 2029
A Study to Assess the Safety, and Tolerability of Nivolumab + Relatlimab Fixed-Dose Combination (FDC) In Unresectable or Metastatic Melanoma Participants In IndiaNCT07459543Nivolumab + RelatlimabPhase 4Locked · track to revealOngoingNot yet recruiting40 est.26 May 2029
View all trials2,164

Track your drug now for free

We check every one of its trials daily and tell you what moved.

  • Status changeStatus moved to completedWas recruiting · always alerts
  • Completion date movePrimary completion slipped 210 daysSlips and pull-ins of 30+ days
  • New trialNew trial registered in your scopeFirst posted within 30 days
  • Enrollment changeEnrollment grew to 1,200Moves of 15%+ or count finalised
  • Substantive record editPrimary endpoint redefined from 24 to 52 weeksRead overnight and flagged in plain English
US registryClinicalTrials.gov
EU registryCTIS · Soon
2,164

Trials as lead sponsor

129

Recruiting now

396

Phase 3 trials

606

Phase 2 trials

859

Phase 1 trials

57

Phase 4 trials