ComplyRx

Immunology & inflammation · Live ClinicalTrials.gov data

Guselkumab (Tremfya) clinical trial pipeline

The timeline below tracks the 16 largest phase 2–4 guselkumab (Tremfya) trials on ClinicalTrials.gov by enrolment, 3 of them actively recruiting. The next phase 3 primary completion among them is expected Mar 2027. Refreshed daily. Add up to four competitors to compare pipelines side by side.

16+

Major trials tracked

11

Phase 3 trials

3

Actively recruiting

Mar 2027

Next phase 3 primary completion

7,161

Participants across trials

Janssen Research & Development, LLC

Lead sponsor by trial count

guselkumab (16)7 active2012–2033
guselkumab
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingCompleted
'12
'14
'16
'18
'20
'22
'24
'26
'28
'30
'32
guselkumab
A Study of the Effectiveness and Safety of Ustekinumab (STELARA) and CNTO 1959 Administered Under the Skin of Patients With Active Rheumatoid Arthritis, Despite Existing Methotrexate TherapyP2
VOYAGE 1P3
An Efficacy and Safety of Guselkumab in Participants With Palmoplantar PustulosisP3
A Study Evaluating the Efficacy and Safety of Guselkumab Administered Subcutaneously in Participants With Active Psoriatic ArthritisP3
Discover-1P3
IXORA-RP4
VEGAP2
COSMOSP3
VISIBLEP3
DUET-CDP2
ASTROP3
DUET-UCP2
FUZION CDP3
TRILOGYP3
CHARGEP3
A Phase 3 Clinical Study of QL2106 InjectionP3

Upcoming readouts

4 ahead · guselkumab

Select a trial to load its full ClinicalTrials.gov record.

Key guselkumab trials

Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.

TrialTitlePhaseStatusPrimary completion
NCT03573323IXORA-R: A Study of Ixekizumab (LY2439821) Compared to Guselkumab in Participants With Moderate-to-Severe…Phase 4CompletedJul 2019
NCT07511647A Phase 3 Clinical Study of QL2106 InjectionPhase 3RecruitingDec 2027
NCT07499232CHARGE: A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Cro…Phase 3RecruitingNov 2028
NCT06663332TRILOGY: A Long-term Extension (LTE) Study of Guselkumab in Pediatric ParticipantsPhase 3RecruitingDec 2031
NCT05528510ASTRO: A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Coli…Phase 3Active, not recruitingApr 2024
NCT05347095FUZION CD: A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's DiseasePhase 3Active, not recruitingMar 2027
NCT02207231VOYAGE 1: A Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psori…Phase 3CompletedSept 2015
NCT02641730An Efficacy and Safety of Guselkumab in Participants With Palmoplantar PustulosisPhase 3CompletedMar 2017
NCT03158285A Study Evaluating the Efficacy and Safety of Guselkumab Administered Subcutaneously in Particip…Phase 3CompletedFeb 2019
NCT03162796Discover-1: A Study Evaluating the Efficacy and Safety of Guselkumab Administered Subcutaneously in Particip…Phase 3CompletedMar 2019
NCT03796858COSMOS: A Study of Guselkumab in Participants With Active Psoriatic Arthritis and an Inadequate Response…Phase 3CompletedNov 2020
NCT05272150VISIBLE: Study of Guselkumab in Skin of Color Participants With Moderate-to-severe Plaque and/or Scalp Ps…Phase 3CompletedMay 2025

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FAQ

How many clinical trials are running for guselkumab?
ClinicalTrials.gov lists more than 16 phase 2–4 guselkumab trials. This page tracks the 16 largest by enrolment: 4 phase 2, 11 phase 3, and 1 phase 4 among them, with 3 actively recruiting. Updated daily.
Are there clinical trials for Tremfya?
Tremfya is the brand name for guselkumab, so guselkumab trials on ClinicalTrials.gov cover it. ClinicalTrials.gov lists more than 16 phase 2–4 guselkumab trials. This page tracks the 16 largest by enrolment: 4 phase 2, 11 phase 3, and 1 phase 4 among them, with 3 actively recruiting. Updated daily.
Where does this data come from?
All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare guselkumab against other drugs?
Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
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