Big pharma · SNY · 2,335 trials led

Sanofi clinical trial pipeline

2,335 trials as lead sponsor, 86 recruiting now, 793 in phase 3. Live from ClinicalTrials.gov, updated daily.

  • Status changeStatus moved to completedWas recruiting · always alerts
  • Completion date movePrimary completion slipped 210 daysSlips and pull-ins of 30+ days
  • New trialNew trial registered in your scopeFirst posted within 30 days
  • Enrollment changeEnrollment grew to 1,200Moves of 15%+ or count finalised
  • Substantive record editPrimary endpoint redefined from 24 to 52 weeksRead overnight and flagged in plain English
View trials

Archive historyOct 2022 to Sept 2026

77 recorded changes across Sanofi trials

Every status move, completion date shift and enrollment change ComplyRx has recorded across 33 of these trials. One is shown below.

Completion date movePrimary completion moved 1,318 days earlierNCT07222189 · recorded 16 Sept 2026
Track to read them

+73 more recorded changes · Track a drug to see every change the night it lands

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Most active programmes

The drugs appearing most often across Sanofi's recently active trials. Comparator arms are excluded.

  • Amlitelimab9 trials
  • Dupilumab7 trials
  • Belumosudil5 trials
  • Lunsekimig4 trials
  • Dexamethasone4 trials
  • Duvakitug3 trials

Upcoming readouts

Next primary completion dates among Sanofi's active phase 2 and phase 3 trials. Dates are registry estimates and move often, which is exactly what the tracker watches.

Top therapeutic areas

Conditions studied most often across Sanofi's recently active trials.

  • Dermatitis Atopic8 trials
  • Chronic Obstructive Pulmonary Disease4 trials
  • Asthma4 trials
  • Atopic Dermatitis4 trials
  • Chronic Graft Versus Host Disease3 trials
  • Multiple Sclerosis3 trials

Sanofi pipeline by phase

The main study drugs across 152 active trials Sanofi leads on ClinicalTrials.gov. Each drug sits in the highest phase among its currently active trials, which can be lower than a phase it has already completed.

Phase 321 drugs

Sanofi phase 3 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
Rilzabrutinib74Nov 2026 est.NCT07216079 · NCT07190196 · NCT07086976
Amlitelimab6Sept 2026 est.NCT06407934 · NCT06241118 · NCT06557772
Frexalimab63Dec 2026 est.NCT07325292 · NCT06141486 · NCT06141473
Lunsekimig62Jun 2027 est.NCT07793409 · NCT07190222 · NCT07190209
Duvakitug54May 2028 est.NCT07185009 · NCT07184996 · NCT07184944
PCV21 vaccine51May 2027 est.NCT07348692 · NCT06975878 · NCT06824194
Itepekimab (SAR440340)4Oct 2026 est.NCT07424144 · NCT06834360 · NCT06834347
Fitusiran31Nov 2026 est.NCT07285460 · NCT05662319 · NCT03754790
venglustat (GZ402671)3Oct 2026 est.NCT05280548 · NCT05206773 · NCT02843035
Isatuximab SAR6509842Apr 2027 est.NCT04270409 · NCT03319667
PCV2121Dec 2026 est.NCT07247188 · NCT06838000
Riliprubart21Jul 2027 est.NCT06290141 · NCT06290128
efanesoctocog alfa (BIVV001)1Jan 2027 est.NCT04644575
Isatuximab SC1NCT05405166
MenACYW conjugate vaccine1NCT07135986
Meningococcal Polysaccharide (Serogroups A, C, W, and Y) Tetanus Toxoid Conjugate Vaccine1NCT04936685
MenQuadfi® (Meningococcal Polysaccharide [Serogroups A, C, W, and Y] Tetanus Toxoid Conjugate Vaccine) (Sanofi Pasteur Inc., Swiftwater, PA, USA)11Mar 2028 est.NCT07710872
Riliprubart Prefilled Pen (PFP)1Oct 2029 est.NCT06859099
Tolebrutinib1Apr 2029 est.NCT06372145
Venglustat1NCT05222906
Yellow fever vaccine (live)11NCT07103148

Phase 220 drugs

Sanofi phase 2 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
BrivekimigSAR44297043Dec 2026 est.NCT07170917 · NCT06975722 · NCT06958536
BalinatunfibSAR4415663Sept 2026 est.NCT07222189 · NCT06867094 · NCT06637631
Isatuximab21Sept 2027 est.NCT05704049 · NCT04643002
SAR441344 IV2NCT05039840 · NCT04879628
SAR44587722Jan 2027 est.NCT07692204 · NCT05584670
Yellow fever vaccine (produced on serum-free Vero cells)2NCT05011123 · NCT04942210
Acne mRNA (messenger ribonucleic acid) vaccine1Jul 2028 est.NCT07756957
Bivalent RSV+HMPV protein vaccine1Jul 2028 est.NCT07810010
BIVV020 (SAR445088)1NCT05156710
Blood draw for the laboratory assessment1Jun 2031 est.NCT02065011
Isatuximab intravenous (IV)1Nov 2028 est.NCT05669989
Isatuximab SC-OBDS11Jan 2027 est.NCT06356571
Long term follow up in all patients who received SAR422459 in previous study TDU135831Aug 2033 est.NCT01736592
Rilzabrutinib dose 111NCT06984627
SAR4431221NCT05588843

Phase 119 drugs

Sanofi phase 1 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
Acne mRNA vaccine22Nov 2028 est.NCT07013747 · NCT06316297
SAR44850122Jan 2028 est.NCT06647069 · NCT06392477
Chlamydia mRNA Vaccine11Jan 2028 est.NCT06891417
Dupilumab coformulated with berahyaluronidase alfa1Sept 2026 est.NCT07646548
Flu H5 egg pandemic low dose vaccine, with adjuvant11Feb 2028 est.NCT07779408
H5 Flu Investigational Medical Product (IMP) 111Apr 2027 est.NCT07516418
Investigational hMPV/RSV vaccine1Jan 2027 est.NCT06686654
Pandemic flu H5 HA mRNA SD2 vaccine1Dec 2026 est.NCT06907511
Pentavalent Meningococcal ABCYW vaccine1May 2027 est.NCT06647407
RSV+HMPV vaccine11May 2028 est.NCT07734649

Phase 410 drugs

Sanofi phase 4 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
Dupilumab167Sept 2026 est.NCT07053423 · NCT06101095 · NCT05983068
Belumosudil62Sept 2026 est.NCT07135973 · NCT07771439 · NCT06143891
teplizumab32Mar 2028 est.NCT05757713 · NCT07088068 · NCT06791291
Avalglucosidase alfa21May 2028 est.NCT06666413 · NCT04910776
Avalglucosidase alfa (GZ402666)2Jun 2027 est.NCT05164055 · NCT03019406
Efanesoctocog alfa11Oct 2027 est.NCT06941870
Fitusiran (SAR439774)11May 2028 est.NCT06145373
iGlarLixi (insulin glargine/lixisenatide)11Sept 2026 est.NCT06671587

Derived from 152 active trials Sanofi leads; 150 name an intervention, folding into 70 phased drugs. 5 interventions carry no registry phase (observational studies, tests and devices) and are not shown. This is ComplyRx's reading of the registry, not Sanofi's own pipeline disclosure.

Sanofi trials

The 50 most significant of Sanofi's recently active trials, soonest estimated readout first.
Select any row for the full record; the change timeline unlocks with tracking.

TrialPhaseStabilityStatusEnrollmentEst. readout
Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male ParticipantsNCT07726914BelumosudilPhase 1Not yet scoredOngoingNot yet recruiting58 est.28 Sept 2026
A Study to Investigate the Long-term Safety, Tolerability and Efficacy of Balinatunfib in Participants With Crohn's Disease or Ulcerative Colitis (SPECIFI-IBD-LTS)NCT07222189balinatunfibPhase 2Locked · track to revealOngoingActive, not recruiting325 est.30 Sept 2026
Pharmacokinetics and Tolerability of Subcutaneous Dupilumab Coformulated With Berahyaluronidase Alfa and Dupilumab Without Berahyaluronidase Alfa in Healthy ParticipantsNCT07646548Dupilumab coformulated with berahyaluronidase alfaPhase 1Locked · track to revealOngoingActive, not recruiting40 est.30 Sept 2026
LEAPVenglustat in Combination With Cerezyme in Adult Patients With Gaucher Disease Type 3 With Venglustat Monotherapy ExtensionNCT02843035venglustat (GZ402671)Phase 2Locked · track to revealOngoingActive, not recruiting12 est.30 Oct 2026
Real-World Study of Patients With Type 1 Diabetes Treated With Teplizumab as Part of Managed Access Programs (MAPs)NCT07457580TeplizumabNot yet scoredOngoingRecruiting60 est.30 Nov 2026
RESULTA Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change DiseaseNCT06500702frexalimabPhase 2Locked · track to revealOngoingRecruiting84 est.23 Dec 2026
Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)NCT07038473Investigational ProcedureNaLocked · track to revealOngoingRecruiting3,500 est.25 Dec 2026
XTEND-edLong-term Safety and Efficacy of Efanesoctocog Alfa (BIVV001) in Previously Treated Patients With Hemophilia ANCT04644575efanesoctocog alfa (BIVV001)Phase 3Locked · track to revealOngoingActive, not recruiting261 est.15 Jan 2027
BRIGHTENBrivekimig for the Treatment of Moderate to Severe Hidradenitis SuppurativaNCT07170917BrivekimigPhase 2Locked · track to revealOngoingRecruiting208 est.9 Feb 2027
CEREN-3An Extension Study to Investigate the Long-term Safety and Tolerability of Itepekimab in Adult Participants With Inadequately Controlled Chronic Rhinosinusitis With Nasal PolypsNCT07424144Itepekimab (SAR440340)Phase 3Locked · track to revealOngoingActive, not recruiting59 est.17 Feb 2027
GLOBOSTADObservational Study of Patients Receiving Dupixent® for Atopic Dermatitis (AD)NCT03992417Dupilumab SAR231893 (REGN668)Locked · track to revealOngoingActive, not recruiting955 est.31 Mar 2027
FREXALTEfficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple SclerosisNCT06141473FrexalimabPhase 3Locked · track to revealOngoingActive, not recruiting1,655 est.6 May 2027
ORBIT-CIDPReal-world Study of Treatment Outcomes in Chronic Inflammatory Demyelinating Polyneuropathy/Polyradiculoneuropathy (CIDP)NCT06968975Not yet scoredOngoingRecruiting200 est.17 May 2027
A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular DegenerationNCT06660667SAR402663Phase 1Locked · track to revealOngoingActive, not recruiting66 est.18 May 2027
DERMIND-ADThe Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic DermatitisNCT07467564DupilumabLocked · track to revealOngoingRecruiting184 est.24 May 2027
Avalglucosidase Alfa French Post-trial Access for Participants With Pompe Disease (PTA Avalglucosidase)NCT05164055Avalglucosidase alfa (GZ402666)Phase 4Locked · track to revealOngoingActive, not recruiting17 est.30 Jun 2027
VITALIZEA Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)NCT06290141riliprubartPhase 3Locked · track to revealOngoingRecruiting160 est.9 Jul 2027
FrexciteNon-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple SclerosisNCT07325292FrexalimabPhase 3Locked · track to revealOngoingRecruiting160 est.15 Jul 2027
LIBRAThe Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell DiseaseNCT06975865RilzabrutinibPhase 3Locked · track to revealOngoingRecruiting192 est.23 Jul 2027
CLAROSA Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis SuppurativaNCT07225569SAR445399Phase 2Locked · track to revealOngoingRecruiting144 est.22 Sept 2027
AQUAA Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK InhibitorNCT06241118AmlitelimabPhase 3Locked · track to revealOngoingActive, not recruiting464 est.30 Sept 2027
CEREN-4A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Adult Japanese Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal PolypsNCT07484230Itepekimab (SAR440340)Phase 3Locked · track to revealStoppedWithdrawn0 est.20 Oct 2027
A Study to Access Activity and Safety With SAR445399 Compared With Placebo in Participants Aged 18 to 80 Years of Age With Non-Cystic Fibrosis BronchiectasisNCT07547436SAR445399Phase 2Locked · track to revealOngoingSuspended70 est.29 Oct 2027
Post Marketing Surveillance Study for MenQuadfi® [Meningococcal (Groups A, C, Y, W) Polysaccharide Tetanus Toxoid Conjugate Vaccine] Administered in Participants Aged 6 Weeks to 55 Years in Republic of KoreaNCT07621653Meningococcal (Groups A, C, Y, W) Polysaccharide Tetanus Toxoid Conjugate VaccineNot yet scoredOngoingRecruiting706 est.23 Nov 2027
Study to Assess Safety and Immunogenicity of an Egg-based H5N8 Influenza Vaccine at Multiple Dose Levels Adjuvanted With Matrix-M in Healthy Participants 18 Years of Age and Above.NCT07779408Flu H5 egg pandemic low dose vaccine, with adjuvantPhase 1Locked · track to revealOngoingRecruiting640 est.22 Feb 2028
Immunogenicity and Safety Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Healthy Infants and Toddlers in ChinaNCT07710872MenQuadfi® (Meningococcal Polysaccharide [Serogroups A, C, W, and Y] Tetanus Toxoid Conjugate Vaccine) (Sanofi Pasteur Inc., Swiftwater, PA, USA)Phase 3Locked · track to revealOngoingRecruiting4,568 est.13 Mar 2028
AD-BEASCUITSA Study to Observe How Pediatric Patients With Severe Atopic Dermatitis Despite Less Extensive Skin Lesions Respond to Dupilumab TreatmentNCT06192563DupilumabLocked · track to revealOngoingRecruiting230 est.31 Mar 2028
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and OlderNCT07734649RSV+HMPV vaccinePhase 1Not yet scoredOngoingRecruiting2,400 est.3 May 2028
SUNSCAPE-1An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative ColitisNCT07184996DuvakitugPhase 3Locked · track to revealOngoingRecruiting980 est.9 May 2028
LUMINA 3A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic AnemiaNCT07086976rilzabrutinibPhase 3Locked · track to revealOngoingRecruiting90 est.31 May 2028
βETA PRESERVEA Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 DiabetesNCT07088068TeplizumabPhase 3Locked · track to revealOngoingRecruiting723 est.6 Jun 2028
AURALIGHTA Study to Investigate Efficacy and Safety of Duvakitug in Adult Participants With Moderate to Severe Hidradenitis SuppurativaNCT07812116DuvakitugPhase 2Not yet scoredOngoingNot yet recruiting156 est.16 Jun 2028
RILIEFA 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related DiseaseNCT07190196RilzabrutinibPhase 3Locked · track to revealOngoingRecruiting124 est.28 Jun 2028
Phase 2b Study of a Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Protein Vaccine Candidate in Adults 60 Years of Age and OlderNCT07810010Bivalent RSV+HMPV protein vaccinePhase 2Not yet scoredOngoingRecruiting8,000 est.3 Jul 2028
Safety of the Acne mRNA Vaccine in Adolescents 12 to 17 Years of Age With Moderate to Severe AcneNCT07756957Acne mRNA (messenger ribonucleic acid) vaccinePhase 2Not yet scoredOngoingNot yet recruiting410 est.19 Jul 2028
A Dose Optimization/Expansion Study of SAR445877 in Adult Chinese Participants With Advanced Gastric or Gastroesophageal Junction CancerNCT07692204SAR445877Phase 2Not yet scoredOngoingRecruiting30 est.2 Aug 2028
SUNSCAPE-2A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative ColitisNCT07185009DuvakitugPhase 3Locked · track to revealOngoingRecruiting751 est.21 Sept 2028
schoolROCKA Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK)NCT07116031BelumosudilPhase 2Locked · track to revealOngoingRecruiting37 est.25 Sept 2028
OPALSPhase 1b/2 Study of IV Sarilumab in Adult With RANCT07704580Sarilumab, SAR153191 SCPhase 1Not yet scoredOngoingRecruiting140 est.26 Oct 2028
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe AcneNCT06316297Acne mRNA vaccinePhase 1Locked · track to revealOngoingRecruiting800 est.30 Nov 2028
International Treatment-extension Study in Adult Participants With Multiple Myeloma and Who Have Derived Clinical Benefit From IsatuximabNCT05669989Isatuximab intravenous (IV)Phase 2Locked · track to revealOngoingEnrolling by invitation70 est.30 Nov 2028
Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)NCT06191315DupilumabPhase 3Locked · track to revealOngoingEnrolling by invitation90 est.21 Dec 2028
A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD)NCT06192576Olipudase alfaNot yet scoredOngoingRecruiting10 est.2 Jan 2029
RIVER-ADLong-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical TrialsNCT05492578AmlitelimabPhase 2Locked · track to revealOngoingActive, not recruiting1,856 est.22 Jan 2029
AIRITYA Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical PracticeNCT07556159Procedure: Investigational ProceduresNot yet scoredOngoingRecruiting2,500 est.4 Apr 2029
A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.NCT06372145TolebrutinibPhase 3Locked · track to revealOngoingActive, not recruiting2,500 est.30 Apr 2029
A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Autoimmune Rheumatic DiseasesNCT06647069SAR448501Phase 1Locked · track to revealOngoingRecruiting62 est.25 Jun 2029
STRIDEThe Study of Chronic Obstructive Pulmonary Disease (COPD) Participants Treated With Dupilumab (STRIDE) RegistryNCT07612878Cohort 1: DupilumabLocked · track to revealOngoingRecruiting350 est.30 Jun 2029
TREMHANCEA Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's DiseaseNCT07688213SAR448851Phase 2Not yet scoredOngoingRecruiting160 est.31 Jul 2029
ATLAS-KIDSA Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male Participants Aged 1 to Less Than 12 Years With Hemophilia A or BNCT07285460FitusiranPhase 3Locked · track to revealOngoingRecruiting85 est.4 Aug 2029
View all trials2,335

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We check every one of its trials daily and tell you what moved.

  • Status changeStatus moved to completedWas recruiting · always alerts
  • Completion date movePrimary completion slipped 210 daysSlips and pull-ins of 30+ days
  • New trialNew trial registered in your scopeFirst posted within 30 days
  • Enrollment changeEnrollment grew to 1,200Moves of 15%+ or count finalised
  • Substantive record editPrimary endpoint redefined from 24 to 52 weeksRead overnight and flagged in plain English
US registryClinicalTrials.gov
EU registryCTIS · Soon
2,335

Trials as lead sponsor

86

Recruiting now

793

Phase 3 trials

638

Phase 2 trials

443

Phase 1 trials

384

Phase 4 trials