10
Phase 2–4 trials
Lipid & Lp(a) therapies · Live ClinicalTrials.gov data
Pelacarsen clinical trial pipeline
ClinicalTrials.gov lists 10 phase 2–4 trials for pelacarsen, 4 of them actively recruiting. The next phase 3 primary completion among them is expected Feb 2028. Refreshed daily. Add up to four competitors to compare pipelines side by side.
8
Phase 3 trials
4
Actively recruiting
Feb 2028
Next phase 3 primary completion
16,504
Participants across trials
Novartis Pharmaceuticals
Lead sponsor by trial count
pelacarsen (10)6 active2017–2032
pelacarsen
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pelacarsen
Phase 2 Study of ISIS 681257 (AKCEA-APO(a)-LRx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular DiseaseP2
Lp(a)HORIZONP3
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Rate of Weekly Lipoprotein Apheresis Sessions in Patients With Hyperlipoproteinemia(a) and Established Cardiovascular Disease in GermanyP3
OLEP3
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve StenosisP2
Lp(a) Lowering Study of Pelacarsen (TQJ230) in US Black/African American and Hispanic Participants With Elevated Lp(a) and Established ASCVDP3
ADD-VANTAGEP3
Pelacarsen Roll-over Extension ProgramP3
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)P3
Lp(a) Lowering Study of Pelacarsen (TQJ230) in Patients in the US With Elevated Lp(a) and Recent ACS (STEMI/NSTEMI) - Lp(a)FRONTIERS PEARLP3
Upcoming readouts
6 ahead · pelacarsen
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Key pelacarsen trials
Top 10 of the 10 registered phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.
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Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.
Related drug pipelines
FAQ
- How many clinical trials are running for pelacarsen?
- ClinicalTrials.gov currently lists 10 phase 2–4 pelacarsen trials: 2 phase 2, 8 phase 3, and 0 phase 4. 4 are actively recruiting.
- Where does this data come from?
- All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
- Can I compare pelacarsen against other drugs?
- Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
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