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inclisiran (16) vs pelacarsen (10)13 active2017–2034
inclisiranpelacarsen
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingCompletedWithdrawn
'17
'19
'21
'23
'25
'27
'29
'31
'33
inclisiran
ORION-3P2
ORION-10P3
ORION-4P3
ORION-8P3
ORION-15P2
V-INITIATEP3
SPIRITP3
V-DIFFERENCEP4
V-PLAQUEP3
V-MonoP3
A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.P4
V-ACCELERATEP4
PRECADP3
LATAM LOWERS LDL-CP4
V-INTERVENTIONP4
ACSP3
pelacarsen
Phase 2 Study of ISIS 681257 (AKCEA-APO(a)-LRx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular DiseaseP2
Lp(a)HORIZONP3
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Rate of Weekly Lipoprotein Apheresis Sessions in Patients With Hyperlipoproteinemia(a) and Established Cardiovascular Disease in GermanyP3
OLEP3
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve StenosisP2
Lp(a) Lowering Study of Pelacarsen (TQJ230) in US Black/African American and Hispanic Participants With Elevated Lp(a) and Established ASCVDP3
ADD-VANTAGEP3
Pelacarsen Roll-over Extension ProgramP3
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)P3
Lp(a) Lowering Study of Pelacarsen (TQJ230) in Patients in the US With Elevated Lp(a) and Recent ACS (STEMI/NSTEMI) - Lp(a)FRONTIERS PEARLP3

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