ComplyRx

Cardiomyopathy & ATTR amyloidosis · Live ClinicalTrials.gov data

Aficamten clinical trial pipeline

ClinicalTrials.gov lists 9 phase 2–4 trials for aficamten, 1 of them actively recruiting. Refreshed daily. Add up to four competitors to compare pipelines side by side.

9

Phase 2–4 trials

5

Phase 3 trials

1

Actively recruiting

2,134

Participants across trials

Cytokinetics

Lead sponsor by trial count

aficamten (9)5 active2020–2031
aficamten
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingEnrolling by invitationCompleted
'20
'21
'22
'23
'24
'25
'26
'27
'28
'29
'30
'31
aficamten
REDWOOD-HCMP2
FOREST-HCMP2
SEQUOIA-HCMP3
MAPLE-HCMP3
ACACIA-HCMP3
An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCMP3
CEDAR-HCMP2
CAMELLIA-HCMP3
CMI-SWITCHP4

Upcoming readouts

3 ahead · aficamten

Select a trial to load its full ClinicalTrials.gov record.

Key aficamten trials

Top 9 of the 9 registered phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.

TrialTitlePhaseStatusPrimary completion
NCT07600177CMI-SWITCH: Mavacamten to Aficamten Transition in Patients With Obstructive Hypertrophic CardiomyopathyPhase 4RecruitingDec 2026
NCT06081894ACACIA-HCM: A Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symp…Phase 3Active, not recruitingAug 2026
NCT07023341CAMELLIA-HCM: A Study to Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic O…Phase 3Active, not recruitingAug 2026
NCT05186818SEQUOIA-HCM: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults Wit…Phase 3CompletedNov 2023
NCT05767346MAPLE-HCM: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate …Phase 3CompletedFeb 2025
NCT06116968An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCMPhase 3CompletedOct 2025
NCT04848506FOREST-HCM: Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adu…Phase 2Enrolling by invitationMar 2028
NCT06412666CEDAR-HCM: A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive H…Phase 2Active, not recruitingJan 2030
NCT04219826REDWOOD-HCM: Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics …Phase 2CompletedFeb 2023

Track aficamten with ComplyRx

Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.

Track aficamten

Related drug pipelines

Compare aficamten vs mavacamtenCompare aficamten vs acoramidis

FAQ

How many clinical trials are running for aficamten?
ClinicalTrials.gov currently lists 9 phase 2–4 aficamten trials: 3 phase 2, 5 phase 3, and 1 phase 4. 1 are actively recruiting.
Where does this data come from?
All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare aficamten against other drugs?
Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
Join the waitlist

Be the first to access ComplyRx

We'll let you know as soon as your spot opens to use ComplyRx.

By joining, you agree to our Privacy Policy.