How many clinical trials are running for aficamten?

ClinicalTrials.gov currently lists 9 phase 2–4 aficamten trials: 3 phase 2, 5 phase 3, and 1 phase 4. 2 are actively recruiting.

Where does this data come from?

All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.

Can I compare aficamten against other drugs?

Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.

Cardiomyopathy & ATTR amyloidosis · Live ClinicalTrials.gov data

Aficamten clinical trial pipeline

ClinicalTrials.gov lists 9 phase 2–4 trials for aficamten, 2 of them actively recruiting. The next phase 3 primary completion among them is expected Aug 2026. Refreshed daily — add up to four competitors to compare pipelines side by side.

Phase 2–4 trials

Phase 3 trials

Actively recruiting

Aug 2026

Next phase 3 primary completion

2,124

Participants across trials

Cytokinetics

Lead sponsor by trial count

aficamten (9)5 active2020–2031

Hide completed

aficamten

Key

Actual date

Anticipated

Forecast to primary completion

RecruitingActive, not recruitingEnrolling by invitationCompleted

'20

'21

'22

'23

'24

'25

'26

'27

'28

'29

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'31

aficamten

REDWOOD-HCMP2

FOREST-HCMP2

SEQUOIA-HCMP3

MAPLE-HCMP3

ACACIA-HCMP3

An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCMP3

CEDAR-HCMP2

CAMELLIA-HCMP3

CMI-SWITCHP4

Upcoming readouts

4 ahead · aficamten

Select a trial to load its full ClinicalTrials.gov record.

Key aficamten trials

Top 9 of the 9 registered phase 2–4 trials, ordered by phase and status. Each links to its full ClinicalTrials.gov record.

Trial	Title	Phase	Status	Primary completion
NCT07600177	CMI-SWITCH — Mavacamten to Aficamten Transition in Patients With Obstructive Hypertrophic Cardiomyopathy	Phase 4	Recruiting	Dec 2026
NCT06081894	ACACIA-HCM — Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic …	Phase 3	Active, not recruiting	Jun 2026
NCT07023341	CAMELLIA-HCM — A Study to Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hyp…	Phase 3	Active, not recruiting	Aug 2026
NCT05186818	SEQUOIA-HCM — Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic …	Phase 3	Completed	Nov 2023
NCT05767346	MAPLE-HCM — Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With…	Phase 3	Completed	Feb 2025
NCT06116968	An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM	Phase 3	Completed	Oct 2025
NCT06412666	CEDAR-HCM — A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Ca…	Phase 2	Recruiting	Jan 2030
NCT04848506	FOREST-HCM — Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM	Phase 2	Enrolling by invitation	Mar 2028
NCT04219826	REDWOOD-HCM — Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 …	Phase 2	Completed	Feb 2023

Compare aficamten vs mavacamten Compare aficamten vs acoramidis

FAQ

How many clinical trials are running for aficamten?: ClinicalTrials.gov currently lists 9 phase 2–4 aficamten trials: 3 phase 2, 5 phase 3, and 1 phase 4. 2 are actively recruiting.
Where does this data come from?: All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare aficamten against other drugs?: Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.

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