9
Phase 2–4 trials
Lipid & Lp(a) therapies · Live ClinicalTrials.gov data
Olezarsen (Tryngolza) clinical trial pipeline
ClinicalTrials.gov lists 9 phase 2–4 trials for olezarsen (Tryngolza), 1 of them actively recruiting. The next phase 3 primary completion among them is expected Mar 2027. Refreshed daily. Add up to four competitors to compare pipelines side by side.
8
Phase 3 trials
1
Actively recruiting
Mar 2027
Next phase 3 primary completion
3,742
Participants across trials
Ionis Pharmaceuticals, Inc.
Lead sponsor by trial count
olezarsen (9)4 active2020–2032
olezarsen
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olezarsen
BALANCEP3
A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe HypertriglyceridemiaP3
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Participants With Familial Chylomicronemia Syndrome (FCS)P3
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With VolanesorsenP3
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe HypertriglyceridemiaP2
A Study of Olezarsen Administered Subcutaneously to Participants With Severe HypertriglyceridemiaP3
A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe HypertriglyceridemiaP3
CORE-OLE: A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG)P3
A Study of Olezarsen for the Treatment of Familial Chylomicronemia Syndrome (FCS) in Pediatric ParticipantsP3
Upcoming readouts
4 ahead · olezarsen
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Key olezarsen trials
Top 9 of the 9 registered phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.
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Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.
Related drug pipelines
FAQ
- How many clinical trials are running for olezarsen?
- ClinicalTrials.gov currently lists 9 phase 2–4 olezarsen trials: 1 phase 2, 8 phase 3, and 0 phase 4. 1 are actively recruiting.
- Are there clinical trials for Tryngolza?
- Tryngolza is the brand name for olezarsen, so olezarsen trials on ClinicalTrials.gov cover it. ClinicalTrials.gov currently lists 9 phase 2–4 olezarsen trials: 1 phase 2, 8 phase 3, and 0 phase 4. 1 are actively recruiting.
- Where does this data come from?
- All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
- Can I compare olezarsen against other drugs?
- Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
