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inclisiran (16) vs olezarsen (8)11 active2017–2034
inclisiranolezarsen
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingCompleted
'17
'19
'21
'23
'25
'27
'29
'31
'33
inclisiran
ORION-3P2
ORION-11P3
ORION-10P3
ORION-4P3
ORION-8P3
Study of Efficacy and Safety of Inclisiran in Asian Participants With Atherosclerotic Cardiovascular Disease (ASCVD) or ASCVD High Risk and Elevated Low Density Lipoprotein Cholesterol (LDL-C)P3
V-INCEPTIONP3
V-INITIATEP3
SPIRITP3
V-PLAQUEP3
A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.P3
V-MonoP3
PRECADP3
LATAM LOWERS LDL-CP4
V-INVINCIBLEP4
V-INTERVENTIONP4
olezarsen
BALANCEP3
A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe HypertriglyceridemiaP3
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Participants With Familial Chylomicronemia Syndrome (FCS)P3
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With VolanesorsenP3
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe HypertriglyceridemiaP2
A Study of Olezarsen Administered Subcutaneously to Participants With Severe HypertriglyceridemiaP3
A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe HypertriglyceridemiaP3
CORE-OLE: A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG)P3

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