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Lipid & Lp(a) therapies · Live ClinicalTrials.gov data

Obicetrapib clinical trial pipeline

ClinicalTrials.gov lists 14 phase 2–4 trials for obicetrapib, 4 of them actively recruiting. The next phase 3 primary completion among them is expected Nov 2026. Refreshed daily. Add up to four competitors to compare pipelines side by side.

14

Phase 2–4 trials

7

Phase 3 trials

4

Actively recruiting

Nov 2026

Next phase 3 primary completion

14,493

Participants across trials

NewAmsterdam Pharma

Lead sponsor by trial count

obicetrapib (14)6 active2021–2029
obicetrapib
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingCompleted
'21
'22
'23
'24
'25
'26
'27
'28
'29
obicetrapib
ROSEP2
OCEANP2
BROADWAYP3
Proof-of-concept, Open-label Study in Patients With Early Alzheimer's DiseaseP2
PREVAILP3
ROSE2P2
A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy.P2
BROOKLYNP3
TANDEMP3
REMBRANDTP3
VINCENTP2
VERMEERP2
RUBENSP3
MEDICIP3

Upcoming readouts

6 ahead · obicetrapib

Select a trial to load its full ClinicalTrials.gov record.

Key obicetrapib trials

Top 12 of the 14 registered phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.

TrialTitlePhaseStatusPrimary completion
NCT07614958MEDICI: Phase 3 Clinical Study Evaluating Efficacy, Safety, and Tolerability of Obicetrapib Vs Bempedoic…Phase 3RecruitingJan 2027
NCT07219602RUBENS: A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetra…Phase 3RecruitingMar 2028
NCT05202509PREVAIL: Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascul…Phase 3Active, not recruitingNov 2026
NCT06305559REMBRANDT: A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary PlaquePhase 3Active, not recruitingNov 2027
NCT05425745BROOKLYN: Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modif…Phase 3CompletedMay 2024
NCT06005597TANDEM: Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modify…Phase 3CompletedSept 2024
NCT05142722BROADWAY: Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifyi…Phase 3CompletedSept 2024
NCT06982508VERMEER: Evaluation of Obicetrapib on Antioxidant Levels in Plasma and HDL Particles of Healthy Volunteer…Phase 2RecruitingSept 2026
NCT06496243VINCENT: Impact of Obicetrapib and Obicetrapib Plus Repatha on Lp(a) LevelsPhase 2RecruitingNov 2026
NCT04770389OCEAN: Randomized Study of Obicetrapib in Combination With EzetimibePhase 2CompletedMay 2021
NCT04753606ROSE: Randomized Study of Obicetrapib as an Adjunct to Statin TherapyPhase 2CompletedMay 2021
NCT05266586ROSE2: Study to Evaluate the Effect of Obicetrapib in Combination With Ezetimibe as an Adjunct to HIS T…Phase 2CompletedAug 2022

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Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.

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Related drug pipelines

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FAQ

How many clinical trials are running for obicetrapib?
ClinicalTrials.gov currently lists 14 phase 2–4 obicetrapib trials: 7 phase 2, 7 phase 3, and 0 phase 4. 4 are actively recruiting.
Where does this data come from?
All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare obicetrapib against other drugs?
Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
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