11
Phase 2–4 trials
MASH / liver disease · Live ClinicalTrials.gov data
Resmetirom (Rezdiffra) clinical trial pipeline
ClinicalTrials.gov lists 11 phase 2–4 trials for resmetirom (Rezdiffra), 3 of them actively recruiting. The next phase 3 primary completion among them is expected Dec 2026. Refreshed daily. Add up to four competitors to compare pipelines side by side.
4
Phase 3 trials
3
Actively recruiting
Dec 2026
Next phase 3 primary completion
5,584
Participants across trials
Madrigal Pharmaceuticals, Inc.
Lead sponsor by trial count
resmetirom (11)8 active2016–2031
resmetirom
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resmetirom
Phase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH)P2
Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)P2
MAESTRO-NASHP3
MAESTRO-NAFLD1P3
A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)P3
A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)P3
REZMASHP4
Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASHP2
A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIVP2
Study of Resmetirom in Children and Adolescents With MASHP2
NOURISH-MASHP4
Upcoming readouts
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Key resmetirom trials
Top 11 of the 11 registered phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.
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Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.
Related drug pipelines
FAQ
- How many clinical trials are running for resmetirom?
- ClinicalTrials.gov currently lists 11 phase 2–4 resmetirom trials: 5 phase 2, 4 phase 3, and 2 phase 4. 3 are actively recruiting.
- Are there clinical trials for Rezdiffra?
- Rezdiffra is the brand name for resmetirom, so resmetirom trials on ClinicalTrials.gov cover it. ClinicalTrials.gov currently lists 11 phase 2–4 resmetirom trials: 5 phase 2, 4 phase 3, and 2 phase 4. 3 are actively recruiting.
- Where does this data come from?
- All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
- Can I compare resmetirom against other drugs?
- Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
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