GLP-1 & incretin therapies · Live ClinicalTrials.gov data

Orforglipron clinical trial pipeline

The timeline below tracks the 16 largest phase 2–4 orforglipron trials on ClinicalTrials.gov by enrolment, 4 of them actively recruiting. The next phase 3 primary completion among them is expected Aug 2027. Refreshed daily. Add up to four competitors to compare pipelines side by side.

16+

Major trials tracked

16

Phase 3 trials

4

Actively recruiting

Aug 2027

Next phase 3 primary completion

27,340

Participants across trials

Eli Lilly and Company

Lead sponsor by trial count

orforglipron (16)10 active2023–2033
orforglipron
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingCompleted
'23
'24
'25
'26
'27
'28
'29
'30
'31
'32
'33
orforglipron
ACHIEVE-4P3
ATTAIN-1P3
ATTAIN-2P3
ACHIEVE-1P3
ACHIEVE-3P3
ACHIEVE-2P3
ATTAIN-OSAP3
A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)P3
A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 DiabetesP3
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One Weight-Related ComorbidityP3
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 DiabetesP3
ATTAIN-OA PAINP3
RESTRAIN-SUIP3
ATTAIN-PADP3
A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)P3
ATTAIN-NOWP3

Upcoming readouts

9 ahead · orforglipron

Select a trial to load its full ClinicalTrials.gov record.

Key orforglipron trials

Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.

TrialTitlePhaseStatusPrimary completion
NCT07202884RESTRAIN-SUI: A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity…Phase 3RecruitingMar 2028
NCT07223593ATTAIN-PAD: Efficacy and Safety of Orforglipron in Participants With Peripheral Artery DiseasePhase 3RecruitingJun 2028
NCT07794579ATTAIN-NOW: A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Relate…Phase 3RecruitingAug 2029
NCT07241390A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Ca…Phase 3RecruitingAug 2031
NCT05869903ATTAIN-1: A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight…Phase 3Active, not recruitingJul 2025
NCT06993792A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With a…Phase 3Active, not recruitingAug 2027
NCT06972459A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One …Phase 3Active, not recruitingAug 2027
NCT06972472A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabet…Phase 3Active, not recruitingAug 2027
NCT06948422A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or …Phase 3Active, not recruitingSept 2027
NCT07153471ATTAIN-OA PAIN: A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthriti…Phase 3Active, not recruitingApr 2028
NCT05971940ACHIEVE-1: A Study of Orforglipron (LY3502970) in Adult Participants With Type 2 Diabetes and Inadequate Gl…Phase 3CompletedApr 2025
NCT05872620ATTAIN-2: A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 DiabetesPhase 3CompletedAug 2025

Track orforglipron with ComplyRx

Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.

Track orforglipron

FAQ

How many clinical trials are running for orforglipron?
ClinicalTrials.gov lists more than 16 phase 2–4 orforglipron trials. This page tracks the 16 largest by enrolment: 0 phase 2, 16 phase 3, and 0 phase 4 among them, with 4 actively recruiting. Updated daily.
Where does this data come from?
All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare orforglipron against other drugs?
Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.

Keep following
what matters.

Choose the drugs, companies or disease areas you follow. Bring trial changes and upcoming readouts into one watch.

Build your watch

Choose what to track in the watch builder.