16+
Major trials tracked
GLP-1 & incretin therapies · Live ClinicalTrials.gov data
Retatrutide clinical trial pipeline
The timeline below tracks the 16 largest phase 2–4 retatrutide trials on ClinicalTrials.gov by enrolment, 3 of them actively recruiting. The next phase 3 primary completion among them is expected Aug 2026. Refreshed daily. Add up to four competitors to compare pipelines side by side.
13
Phase 3 trials
3
Actively recruiting
Aug 2026
Next phase 3 primary completion
25,881
Participants across trials
Eli Lilly and Company
Lead sponsor by trial count
retatrutide (16)11 active2021–2032
retatrutide
'21
'22
'23
'24
'25
'26
'27
'28
'29
'30
'31
'32
retatrutide
A Study of LY3437943 in Participants With Type 2 DiabetesP2
A Study of LY3437943 in Participants Who Have Obesity or Are OverweightP2
TRIUMPH-3P3
TRIUMPH-1P3
TRIUMPH-2P3
TRIUMPH-4P3
Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)P3
Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)P3
Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)P3
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)P3
TRIUMPH-5P3
TRIUMPH-6P3
TRIUMPH-7P3
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)P3
TRIUMPH-9P3
GZBFP2
Upcoming readouts
9 ahead · retatrutide
Select a trial to load its full ClinicalTrials.gov record.
Key retatrutide trials
Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Each links to its full ClinicalTrials.gov record.
| Trial | Title | Phase | Status | Primary completion |
|---|---|---|---|---|
| NCT07035093 | TRIUMPH-7: A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Lo… | Phase 3 | Recruiting | Sept 2027 |
| NCT07165028 | A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic L… | Phase 3 | Recruiting | Aug 2030 |
| NCT05882045 | TRIUMPH-3: A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease | Phase 3 | Active, not recruiting | Apr 2026 |
| NCT05929079 | TRIUMPH-2: A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesit… | Phase 3 | Active, not recruiting | May 2026 |
| NCT06260722 | Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and I… | Phase 3 | Active, not recruiting | Aug 2026 |
| NCT06297603 | Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or… | Phase 3 | Active, not recruiting | Oct 2026 |
| NCT06662383 | TRIUMPH-5: A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesit… | Phase 3 | Active, not recruiting | Dec 2026 |
| NCT06859268 | TRIUMPH-6: A Study of Retatrutide (LY3437943) in the Maintenance of Weight Reduction in Individuals With Ob… | Phase 3 | Active, not recruiting | Apr 2028 |
| NCT07357415 | TRIUMPH-9: A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or O… | Phase 3 | Active, not recruiting | Oct 2028 |
| NCT06383390 | The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults L… | Phase 3 | Active, not recruiting | Feb 2029 |
| NCT05931367 | TRIUMPH-4: A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight an… | Phase 3 | Completed | Nov 2025 |
| NCT06354660 | Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inade… | Phase 3 | Completed | Jan 2026 |
Related drug pipelines
FAQ
- How many clinical trials are running for retatrutide?
- ClinicalTrials.gov lists more than 16 phase 2–4 retatrutide trials. This page tracks the 16 largest by enrolment: 3 phase 2, 13 phase 3, and 0 phase 4 among them, with 3 actively recruiting. Updated daily.
- Where does this data come from?
- All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
- Can I compare retatrutide against other drugs?
- Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
Join the waitlist
Be the first to access ComplyRx
We'll let you know as soon as your spot opens to use ComplyRx.
By joining, you agree to our Privacy Policy.