GLP-1 & incretin therapies · Live ClinicalTrials.gov data

Semaglutide (Ozempic / Wegovy) clinical trial pipeline

The timeline below tracks the 16 largest phase 2–4 semaglutide (Ozempic and Wegovy) trials on ClinicalTrials.gov by enrolment, 4 of them actively recruiting. The next phase 3 primary completion among them is expected Jun 2027. Refreshed daily. Add up to four competitors to compare pipelines side by side.

16+

Major trials tracked

14

Phase 3 trials

4

Actively recruiting

Jun 2027

Next phase 3 primary completion

30,321

Participants across trials

Novo Nordisk A/S

Lead sponsor by trial count

semaglutide (16)9 active20142030
semaglutide
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingNot yet recruitingCompleted
'14
'16
'18
'20
'22
'24
'26
'28
'30
semaglutide
SUSTAIN™ 4P3
SUSTAIN™P3
SUSTAIN 7P3
STEP 3P3
STEP 6P3
STEP7P3
ASCEND PLUSP4
A Phase III Study Comparing the Weight Loss Effects of Semaglutide Injection and Wegovy®P3
A Study of HRS9531 Versus Semaglutide Once Weekly as Add-on Therapy to Metformin Monotherapy or in Combination With SGLT2 Inhibitors in Participants With Type 2 DiabetesP3
A Study of BGM0504 in Participants with Type 2 DiabetesP3
A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney DiseaseP2
Efficacy and Safety of Semaglutide Injection Vs WEGOVY® in Chinese Obese PatientsP3
A Clinical Study Comparing Semaglutide Injection and Wegovy® for Weight Management in Obese SubjectsP3
Phase III Clinical Study on the Efficacy and Safety of Semaglutide and Ozempic® in Patients With Type 2 DiabetesP3
Phase III Clinical Study Comparing the Efficacy and Safety of GZR18 Injection and Semaglutide (Wegovy®) in Adult Obese or Overweight SubjectsP3
AMAZE 8P3

Upcoming readouts

5 ahead · semaglutide

Select a trial to load its full ClinicalTrials.gov record.

Key semaglutide trials

Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.

TrialTitlePhaseStatusPrimary completion
NCT05441267ASCEND PLUS: A Study of Cardiovascular Events iN Diabetes PlusPhase 4Active, not recruitingAug 2028
NCT06716216A Study of BGM0504 in Participants with Type 2 DiabetesPhase 3RecruitingMar 2026
NCT07036172Efficacy and Safety of Semaglutide Injection Vs WEGOVY® in Chinese Obese PatientsPhase 3RecruitingApr 2026
NCT07150975Phase III Clinical Study Comparing the Efficacy and Safety of GZR18 Injection and Semaglutide (W…Phase 3RecruitingJun 2027
NCT06633783A Phase III Study Comparing the Weight Loss Effects of Semaglutide Injection and Wegovy®Phase 3Not yet recruitingMay 2026
NCT06738979A Clinical Study Comparing Semaglutide Injection and Wegovy® for Weight Management in Obese Subj…Phase 3Not yet recruitingJul 2026
NCT07046273Phase III Clinical Study on the Efficacy and Safety of Semaglutide and Ozempic® in Patients With…Phase 3Not yet recruitingAug 2028
NCT07400107AMAZE 8: AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semagluti…Phase 3Not yet recruitingDec 2028
NCT02128932SUSTAIN™ 4: Efficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to M…Phase 3CompletedSept 2015
NCT02254291SUSTAIN™: A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly Versus Sitagliptin Once Dai…Phase 3CompletedNov 2015
NCT02648204SUSTAIN 7: Efficacy and Safety of Semaglutide Versus Dulaglutide as add-on to Metformin in Subjects With Ty…Phase 3CompletedApr 2017
NCT03611582STEP 3: Research Study to Look at How Well Semaglutide is at Lowering Weight When Taken Together With an…Phase 3CompletedMar 2020

Track semaglutide with ComplyRx

Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.

Track semaglutide

FAQ

How many clinical trials are running for semaglutide?
ClinicalTrials.gov lists more than 16 phase 2–4 semaglutide trials. This page tracks the 16 largest by enrolment: 1 phase 2, 14 phase 3, and 1 phase 4 among them, with 4 actively recruiting. Updated daily.
Are there clinical trials for Ozempic and Wegovy?
Ozempic and Wegovy are brand names for semaglutide, so semaglutide trials on ClinicalTrials.gov cover them. ClinicalTrials.gov lists more than 16 phase 2–4 semaglutide trials. This page tracks the 16 largest by enrolment: 1 phase 2, 14 phase 3, and 1 phase 4 among them, with 4 actively recruiting. Updated daily.
Where does this data come from?
All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare semaglutide against other drugs?
Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.
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