How many clinical trials are running for tezepelumab?

ClinicalTrials.gov lists more than 16 phase 2–4 tezepelumab trials. This page tracks the 16 largest by enrolment: 4 phase 2, 11 phase 3, and 1 phase 4 among them, with 5 actively recruiting. Updated daily.

Are there clinical trials for Tezspire?

Tezspire is the brand name for tezepelumab, so tezepelumab trials on ClinicalTrials.gov cover it. ClinicalTrials.gov lists more than 16 phase 2–4 tezepelumab trials. This page tracks the 16 largest by enrolment: 4 phase 2, 11 phase 3, and 1 phase 4 among them, with 5 actively recruiting. Updated daily.

Where does this data come from?

All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.

Can I compare tezepelumab against other drugs?

Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.

Respiratory · Live ClinicalTrials.gov data

Tezepelumab (Tezspire) clinical trial pipeline

The timeline below tracks the 16 largest phase 2–4 tezepelumab (Tezspire) trials on ClinicalTrials.gov by enrolment, 5 of them actively recruiting. The next phase 3 primary completion among them is expected Jun 2027. Refreshed daily. Add up to four competitors to compare pipelines side by side.

16+

Major trials tracked

Phase 3 trials

Actively recruiting

Jun 2027

Next phase 3 primary completion

6,770

Participants across trials

AstraZeneca

Lead sponsor by trial count

tezepelumab (16)8 active2013–2030

Hide completed

tezepelumab

Key

Actual date

Anticipated

Forecast to primary completion

RecruitingActive, not recruitingNot yet recruitingCompletedTerminated

'13

'15

'17

'19

'21

'23

'25

'27

'29

tezepelumab

Study to Evaluate the Efficacy and Safety of MEDI9929 (AMG 157) in Adult Subjects With Inadequately Controlled, Severe AsthmaP2

A Dose Ranging Placebo-Controlled Double-Blind Study to Evaluate the Safety and Efficacy of Tezepelumab in Atopic DermatitisP2

PATH-HOMEP3

DIRECTIONP3

COURSEP2

INCEPTIONP2

WAYPOINTP3

PASSAGEP4

WAYFINDERP3

HORIZONP3

ARRIVALP3

EMBARKP3

JOURNEYP3

Compare the Efficacy and Safety of QL2302 Versus Tezspire® in Severe AsthmaP3

TAPERP3

BIFANGP3

Upcoming readouts

7 ahead · tezepelumab

Select a trial to load its full ClinicalTrials.gov record.

Key tezepelumab trials

Top 12 of the 16 tracked phase 2–4 trials, ordered by phase and status. Trial names open the full ComplyRx trial page; NCT ids link to ClinicalTrials.gov.

Trial	Title	Phase	Status	Primary completion
NCT05329194	PASSAGE: Effectiveness and Safety Study of Tezepelumab in Adults & Adolescent Participants With Severe As…	Phase 4	Completed	Oct 2025
NCT07363642	TAPER: Phase 3b Study in Patients With Severe Asthma Treated With Tezepelumab	Phase 3	Recruiting	Feb 2028
NCT07520162	BIFANG: A Study to Investigate NPS and Symptoms in Chinese Adult Participants With CRSwNP Initiating Tre…	Phase 3	Recruiting	Mar 2028
NCT06023589	HORIZON: A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children …	Phase 3	Recruiting	May 2028
NCT06878261	JOURNEY: A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderat…	Phase 3	Recruiting	Mar 2029
NCT06883305	EMBARK: A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderat…	Phase 3	Recruiting	Mar 2029
NCT06473779	ARRIVAL: Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Con…	Phase 3	Active, not recruiting	Jun 2027
NCT07302516	Compare the Efficacy and Safety of QL2302 Versus Tezspire® in Severe Asthma	Phase 3	Not yet recruiting	Dec 2028
NCT03968978	PATH-HOME: Tezepelumab Home Use Study	Phase 3	Completed	Jun 2020
NCT03927157	DIRECTION: Study to Evaluate Tezepelumab in Adults With Severe Uncontrolled Asthma	Phase 3	Completed	May 2024
NCT05274815	WAYFINDER: Study to Evaluate Efficacy and Safety of Tezepelumab in Reducing Oral Corticosteroid Use in Adul…	Phase 3	Completed	Sept 2024
NCT04851964	WAYPOINT: Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal…	Phase 3	Completed	Sept 2024

Track tezepelumab with ComplyRx

Get an alert when a trial changes status, moves its completion date, or a new trial registers in scope. Checked nightly against ClinicalTrials.gov.

Track tezepelumab

nerandomilast
Respiratory

Compare tezepelumab vs nerandomilast

FAQ

How many clinical trials are running for tezepelumab?: ClinicalTrials.gov lists more than 16 phase 2–4 tezepelumab trials. This page tracks the 16 largest by enrolment: 4 phase 2, 11 phase 3, and 1 phase 4 among them, with 5 actively recruiting. Updated daily.
Are there clinical trials for Tezspire?: Tezspire is the brand name for tezepelumab, so tezepelumab trials on ClinicalTrials.gov cover it. ClinicalTrials.gov lists more than 16 phase 2–4 tezepelumab trials. This page tracks the 16 largest by enrolment: 4 phase 2, 11 phase 3, and 1 phase 4 among them, with 5 actively recruiting. Updated daily.
Where does this data come from?: All trial data is sourced from ClinicalTrials.gov (CTGov) and refreshed on this page daily.
Can I compare tezepelumab against other drugs?: Yes. The free ComplyRx Trial Pipeline tool compares up to five drugs side by side on one timeline, with PNG and PDF export. Add any competitor in the search box above.

Upcoming readouts

Key tezepelumab trials

Track tezepelumab with ComplyRx

Related drug pipelines

FAQ

Keep followingwhat matters.

Keep following
what matters.