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sacituzumab govitecan (16) vs trastuzumab deruxtecan (16)26 active20172035
sacituzumab govitecantrastuzumab deruxtecan
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingNot yet recruitingCompletedTerminated
'17
'19
'21
'23
'25
'27
'29
'31
'33
'35
sacituzumab govitecan
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBCP2
Sacituzumab Govitecan +/- Pembrolizumab In HR+ / HER2 - MBCP2
Scalp Cooling in MBCP2
EVOKE-01P3
ELEVATE TNBCP2
A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)P2
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)P3
Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast CancerP2
Circulating Tumor DNA to Guide Changes in Standard of Care ChemotherapyP2
ASCENT-GYN-01P3
Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)P2
Optimal Application Timing of ADC Drugs for Advanced Breast CancerP2
OASISP2
A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial CancerP3
A Phase III Study of JSKN016 Versus Treatment of Physician's Choice in Patients With Triple-Negative Breast Cancer Who Have Failed Standard of CareP3
SCARLET-ICEP2
trastuzumab deruxtecan
A Study of DS-8201a in Metastatic Breast Cancer Previously Treated With Trastuzumab Emtansine (T-DM1)P2
DS-8201a in Human Epidermal Growth Factor Receptor2 (HER2)-Expressing Colorectal Cancer (DESTINY-CRC01)P2
DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02]P3
DAISYP2
DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02)P2
DG-03P2
A Study of U3-1402 (Patritumab Deruxtecan) in Subjects With Metastatic Breast CancerP2
Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)P3
DG-06P2
Scalp Cooling in MBCP2
Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)P2
Optimal Application Timing of ADC Drugs for Advanced Breast CancerP2
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)P3
TDXdoseP4
Serplulimab Combined With Trastuzumab Rezetecan as Neoadjuvant Therapy for Triple-Negative Breast CancerP2
MEGA-TACT-BC3P3

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