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efruxifermin (6) vs resmetirom (10)11 active2016–2034
efruxiferminresmetirom
Key
Actual date
Anticipated
Forecast to primary completion
RecruitingActive, not recruitingNot yet recruitingCompleted
'16
'18
'20
'22
'24
'26
'28
'30
'32
'34
efruxifermin
A Study of Efruxifermin in Subjects With Histologically Confirmed Nonalcoholic Steatohepatitis (NASH)P2
HarmonyP2
A Study of Efruxifermin in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (Symmetry)P2
A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)P3
A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and FibrosisP3
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASHP3
resmetirom
Phase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH)P2
Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)P2
MAESTRO-NASHP3
MAESTRO-NAFLD1P3
A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)P3
A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)P3
REZMASHP4
Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASHP2
A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIVP2
NOURISH-MASHP4

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