Big pharma · TAK · 1,708 trials led

Takeda clinical trial pipeline

1,708 trials as lead sponsor, 83 recruiting now, 559 in phase 3. Live from ClinicalTrials.gov, updated daily.

  • Status changeStatus moved to completedWas recruiting · always alerts
  • Completion date movePrimary completion slipped 210 daysSlips and pull-ins of 30+ days
  • New trialNew trial registered in your scopeFirst posted within 30 days
  • Enrollment changeEnrollment grew to 1,200Moves of 15%+ or count finalised
  • Substantive record editPrimary endpoint redefined from 24 to 52 weeksRead overnight and flagged in plain English
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Archive historyOct 2022 to Sept 2026

64 recorded changes across Takeda trials

Every status move, completion date shift and enrollment change ComplyRx has recorded across 31 of these trials. One is shown below.

Completion date movePrimary completion moved 153 days earlierNCT06581328 · recorded 16 Sept 2026
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+60 more recorded changes · Track a drug to see every change the night it lands

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Most active programmes

The drugs appearing most often across Takeda's recently active trials. Comparator arms are excluded.

  • Soticlestat14 trials
  • Zasocitinib8 trials
  • TAK-9356 trials
  • Mezagitamab4 trials
  • Elritercept4 trials
  • Vedolizumab3 trials

Upcoming readouts

Next primary completion dates among Takeda's active phase 2 and phase 3 trials. Dates are registry estimates and move often, which is exactly what the tracker watches.

Top therapeutic areas

Conditions studied most often across Takeda's recently active trials.

  • Crohn's Disease9 trials
  • Ulcerative Colitis6 trials
  • Dravet Syndrome (DS)6 trials
  • Lennox-Gastaut Syndrome (LGS)4 trials
  • Narcolepsy Type 14 trials
  • Epilepsy3 trials

Takeda pipeline by phase

The main study drugs across 83 active trials Takeda leads on ClinicalTrials.gov. Each drug sits in the highest phase among its currently active trials, which can be lower than a phase it has already completed.

Phase 319 drugs

Takeda phase 3 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
ZasocitinibTAK-279129Feb 2027 est.NCT07752108 · NCT07286058 · NCT07250802
ElriterceptTAK-22666Feb 2028 est.NCT07623161 · NCT07422480 · NCT06499285
Mezagitamab43Mar 2028 est.NCT06963827 · NCT06948318 · NCT06722235
Fazirsiran Injection32Aug 2028 est.NCT06165341 · NCT05899673 · NCT05677971
MobocertinibTAK-7883Oct 2026 est.NCT04129502 · NCT03807778 · NCT02716116
Maribavir22Dec 2026 est.NCT06439342 · NCT05319353
TAK-75521Mar 2027 est.NCT04683003 · NCT07392450
TAK-86121Oct 2026 est.NCT07363720 · NCT05816382
TAK-88121May 2028 est.NCT06747351 · NCT06076642
TDV22Apr 2027 est.NCT06665035 · NCT06579755
Vonicog Alfa22Nov 2027 est.NCT07129343 · NCT05582993
IGI, 10%11Sept 2028 est.NCT06980480
Ponatinib1NCT03589326
TAK-33011Aug 2028 est.NCT05156983
TAK-92811Nov 2028 est.NCT07217301
Teduglutide1Feb 2027 est.NCT06973304
Tetravalent Dengue Vaccine (TDV)1NCT07047521
Vedolizumab SC11Aug 2030 est.NCT06405087
Vortioxetine tablets11Sept 2029 est.NCT07204314

Phase 25 drugs

Takeda phase 2 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
TAK-36044Nov 2026 est.NCT07646678 · NCT07633301 · NCT06952699
Rusfertide21Oct 2027 est.NCT07765602 · NCT07648030
Idursulfase-IT1Jan 2029 est.NCT06031259
TAK-0071NCT05020015
TAK-41111Dec 2027 est.NCT06798012

Phase 15 drugs

Takeda phase 1 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
AskBio0091Jan 2030 est.NCT01687608
TAK-18811Dec 2028 est.NCT07205718
TAK-50511Aug 2030 est.NCT07436728
TAK-78111Apr 2028 est.NCT07229911
TAK-8531NCT06390995

Phase 47 drugs

Takeda phase 4 drugs, most trials first
DrugTrialsRecruitingNext readoutSample trials
Vedolizumab IV65May 2027 est.NCT06581328 · NCT06100289 · NCT05837897
Vedolizumab54Jun 2027 est.NCT06095128 · NCT06045754 · NCT06443502
Brentuximab vedotin31Mar 2028 est.NCT06831370 · NCT05673785 · NCT02979522
CDPATH™1NCT04809363
Fruquintinib11Oct 2027 est.NCT06562543
Replagal11Oct 2027 est.NCT05067868
TAK-6641Dec 2027 est.NCT07794735

Derived from 83 active trials Takeda leads; 83 name an intervention, folding into 36 phased drugs. 3 interventions carry no registry phase (observational studies, tests and devices) and are not shown. This is ComplyRx's reading of the registry, not Takeda's own pipeline disclosure.

Takeda trials

The 50 most significant of Takeda's recently active trials, soonest estimated readout first.
Select any row for the full record; the change timeline unlocks with tracking.

TrialPhaseStabilityStatusEnrollmentEst. readout
HYPNOSEpidemiology of Narcolepsy Type 1 and Type 2 in SpainNCT07299097Not yet scoredOngoingActive, not recruiting402 est.30 Sept 2026
A Trial of TAK-861 for the Treatment of Narcolepsy With CataplexyNCT07363720TAK-861Phase 3Locked · track to revealOngoingActive, not recruiting98 est.2 Oct 2026
A Survey of Lanadelumab in Participants With Hereditary AngioedemaNCT05397431LanadelumabNot yet scoredOngoingActive, not recruiting155 est.27 Oct 2026
A Study to Learn More About the Treatment of People With Congenital Thrombotic Thrombocytopenic Purpura (cTTP) Who Received Recombinant ADAMTS13 (rADAMTS13) as Part of the Early Access ProgramNCT07429942Not yet scoredOngoingNot yet recruiting94 est.30 Oct 2026
A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2)NCT06952699TAK-360Phase 2Locked · track to revealOngoingRecruiting88 est.30 Nov 2026
A Study of TAK-360 in Adults With Idiopathic HypersomniaNCT06812078TAK-360Phase 2Locked · track to revealOngoingRecruiting96 est.30 Nov 2026
A Study on Infections in Adults With Ulcerative Colitis/Crohn's DiseaseNCT07250815Not yet scoredOngoingNot yet recruiting23,900 est.15 Dec 2026
A Study of OBIZUR in Adults With Acquired Hemophilia A (AHA) in South KoreaNCT06550882OBIZURNot yet scoredOngoingRecruiting9 est.31 Dec 2026
Post-Marketing Study of Prucalopride Safety In PregnancyNCT04869280Not yet scoredOngoingActive, not recruiting125 est.1 Feb 2027
A Study of Teduglutide in Chinese Adults With Short Bowel SyndromeNCT06973304TeduglutidePhase 3Locked · track to revealOngoingActive, not recruiting13 est.10 Feb 2027
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's DiseaseNCT06233461TAK-279Phase 2Locked · track to revealOngoingRecruiting268 est.17 Feb 2027
PANORAMAA Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community SettingNCT06581328Vedolizumab IVPhase 4Locked · track to revealOngoingRecruiting200 est.1 May 2027
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic MedicinesNCT06671483ZasocitinibPhase 3Locked · track to revealOngoingRecruiting1,088 est.18 May 2027
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic MedicinesNCT06671496ZasocitinibPhase 3Locked · track to revealOngoingRecruiting600 est.18 May 2027
A Study of Zasocitinib in Adults With Non-pustular Palmoplantar PsoriasisNCT07752108ZasocitinibPhase 3Not yet scoredOngoingNot yet recruiting40 est.30 May 2027
A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's DiseaseNCT06045754VedolizumabPhase 4Locked · track to revealOngoingRecruiting50 est.28 Jun 2027
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)NCT06095128VedolizumabPhase 4Locked · track to revealOngoingRecruiting65 est.9 Jul 2027
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal CancerNCT06562543FruquintinibPhase 4Locked · track to revealOngoingRecruiting78 est.4 Oct 2027
A Study of Zasocitinib in Adults With Nonsegmental VitiligoNCT07108283ZasocitinibPhase 2Locked · track to revealOngoingRecruiting200 est.12 Oct 2027
A Study of Rusfertide in Japanese Adults With Polycythemia VeraNCT07648030RusfertidePhase 2Not yet scoredOngoingRecruiting9 est.28 Oct 2027
A Study of Replagal in Children and Adults With Fabry Disease in IndiaNCT05067868ReplagalPhase 4Locked · track to revealOngoingRecruiting5 est.31 Oct 2027
A Study of TAK-664 in People With Primary Immunodeficiency Diseases Who Have Not Yet Been Treated With ImmunoglobulinsNCT07794735TAK-664Phase 4Not yet scoredOngoingNot yet recruiting9 est.1 Dec 2027
A Study of TAK-755 in Adults With Acute Ischemic StrokeNCT07392450TAK-755Phase 2Locked · track to revealOngoingRecruiting222 est.6 Dec 2027
A Study of Mezagitamab in Adults With Chronic Primary Immune ThrombocytopeniaNCT06722235MezagitamabPhase 3Locked · track to revealOngoingRecruiting171 est.16 Mar 2028
A Study of Zasocitinib (TAK-279) in Adults With Active Crohn's DiseaseNCT07403968ZasocitinibPhase 2Locked · track to revealOngoingRecruiting20 est.30 Mar 2028
A Study of Fruquintinib in Adults With Metastatic Colorectal Cancer in PolandNCT07623174Not yet scoredOngoingNot yet recruiting110 est.31 Mar 2028
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood TransfusionsNCT06499285ElriterceptPhase 3Locked · track to revealOngoingRecruiting225 est.1 May 2028
A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's DiseaseNCT06100289Vedolizumab IVPhase 3Locked · track to revealOngoingRecruiting70 est.16 May 2028
A Survey of Susoctocog Alfa (Genetical Recombination) in Participants With Acquired Haemophilia ANCT06461533Susoctocog Alfa (Genetical Recombination)Not yet scoredOngoingRecruiting25 est.31 May 2028
A Study of TAK-226 for Anemia in Japanese Patients With Lower-Risk Myelodysplastic SyndromesNCT07319845TAK-226Phase 2Locked · track to revealOngoingRecruiting42 est.26 Jun 2028
A Survey of Maribavir Tablets in Participants With Cytomegalovirus InfectionNCT06577363MaribavirNot yet scoredOngoingRecruiting250 est.30 Jun 2028
A Study of Rusfertide in Adults With Polycythemia Vera in ChinaNCT07765602RusfertidePhase 2Not yet scoredOngoingNot yet recruiting24 est.1 Jul 2028
A Study of Mezagitamab in Adults With Kidney Condition Called IgA NephropathyNCT06963827MezagitamabPhase 3Locked · track to revealOngoingRecruiting347 est.7 Sept 2028
A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple MyelomaNCT06980480IGI, 10%Phase 3Locked · track to revealOngoingRecruiting183 est.11 Sept 2028
Gaucher Disease Outcome Survey (GOS)NCT03291223Not yet scoredOngoingRecruiting1,257 est.30 Sept 2028
MarsLight-11A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung CancerNCT07217301TAK-928Phase 3Locked · track to revealOngoingRecruiting600 est.1 Nov 2028
A Study of TAK-188 in Adults With Advanced or Spreading Solid TumorsNCT07205718TAK-188Phase 1Locked · track to revealOngoingRecruiting223 est.26 Dec 2028
A Study of Mezagitamab in Adults With Late Antibody-Mediated Rejection (AMR) After a Kidney TransplantNCT07613359MezagitamabPhase 2Locked · track to revealOngoingNot yet recruiting36 est.15 Jan 2029
ELRiSE MDSA Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood TransfusionsNCT07422480ElriterceptPhase 3Locked · track to revealOngoingRecruiting300 est.30 Apr 2029
A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune ThrombocytopeniaNCT06948318MezagitamabPhase 3Locked · track to revealOngoingRecruiting150 est.29 Jul 2029
A Study of Vortioxetine in Japanese Pediatric Patients With Major Depressive DisorderNCT07204314Vortioxetine tabletsPhase 3Locked · track to revealOngoingRecruiting180 est.30 Sept 2029
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS)NCT04419649ElriterceptPhase 2Locked · track to revealOngoingRecruiting160 est.30 Oct 2029
ELRISE MFA Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking RuxolitinibNCT07623161ElriterceptPhase 3Not yet scoredOngoingRecruiting324 est.7 Dec 2029
Continuation Study of Zasocitinib in Adults With Psoriatic ArthritisNCT07286058ZasocitinibPhase 3Locked · track to revealOngoingRecruiting1,182 est.18 Dec 2029
A Study to Learn About the Safety of Vedolizumab and How Well it Works in Children and Teenagers With Active Chronic PouchitisNCT06443502VedolizumabPhase 3Locked · track to revealOngoingRecruiting30 est.31 Jan 2030
A Database Survey to Evaluate the Safety of Immune Globulin Subcutaneous (Human), 20% Solution in Participants With Primary ImmunodeficiencyNCT06565078Immune Globulin Subcutaneous (Human), 20% SolutionNot yet scoredOngoingRecruiting100 est.31 Mar 2030
A Study of Vonicog Alfa (rVWF) in Children With Severe Von Willebrand Disease (vWD)NCT05582993Vonicog AlfaPhase 3Locked · track to revealOngoingRecruiting24 est.11 Apr 2030
A Study of Freeze-dried Human Protein C Concentrate (TAK-662) in Participants With Congenital Protein C DeficiencyNCT06590974Freeze-dried Human Protein C ConcentrateNot yet scoredOngoingRecruiting7 est.30 Jun 2030
A Study of TAK-505 in Adults With Solid TumorsNCT07436728TAK-505Phase 1Locked · track to revealOngoingRecruiting151 est.18 Aug 2030
A Study of TAK-360 in People With Narcolepsy or Idiopathic HypersomniaNCT07646678TAK-360Phase 2Not yet scoredOngoingRecruiting500 est.15 Jun 2031
View all trials1,708

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We check every one of its trials daily and tell you what moved.

  • Status changeStatus moved to completedWas recruiting · always alerts
  • Completion date movePrimary completion slipped 210 daysSlips and pull-ins of 30+ days
  • New trialNew trial registered in your scopeFirst posted within 30 days
  • Enrollment changeEnrollment grew to 1,200Moves of 15%+ or count finalised
  • Substantive record editPrimary endpoint redefined from 24 to 52 weeksRead overnight and flagged in plain English
US registryClinicalTrials.gov
EU registryCTIS · Soon
1,708

Trials as lead sponsor

83

Recruiting now

559

Phase 3 trials

373

Phase 2 trials

411

Phase 1 trials

124

Phase 4 trials