AP

Alnylam Pharmaceuticals

Every trial this sponsor leads in the registry, and everything it has published.

71All trials
Recruiting17
Recruited4
By invitation1
Completed40
Stopped9

22 active · 31% of this sponsor’s registry footprint

Cardiovascular6 trials
Neurology5 trials
Metabolic/Endocrine/Nutrition4 trials
Genetic & Rare Disease1 trial
Haematology1 trial
Oncology1 trial
Ophthalmology1 trial

Not shown above: 2 Phase 1 healthy-volunteer trials and 1 trial whose condition matched no therapy area.

Trials by phase

Phase 134
Phase 220
Phase 315
Unphased2

Pipeline by phase · 13 drugs in active development

Phase 3 · 3 drugs

Nucresiran2 trials · 2 recruitingest. Dec 2027
Vutrisiran2 trialsest. Mar 2028
Zilebesiran1 trial · 1 recruitingest. Sept 2030

Phase 2 · 4 drugs

ALN-43242 trials · 1 recruitingest. May 2027
ALN-64002 trials · 1 recruitingest. Jun 2027
ALN-APP2 trials · 1 recruitingest. Aug 2027
ALN-AGT01 RVR1 trial · 1 recruitingest. Apr 2028

Phase 1 · 6 drugs

ALN-22321 trial · 1 recruitingest. Apr 2027
ALN-42851 trial · 1 recruitingest. Dec 2026
ALN-49151 trial · 1 recruitingest. Jul 2027
ALN-52881 trial · 1 recruitingest. Mar 2030
ALN-BCAT1 trial · 1 recruitingest. Sept 2027
ALN-HTT021 trial · 1 recruitingest. Jul 2028

Active trials only, code names and brands merged. 40 completed trials are in the counts above but their drugs are not folded into this pipeline.

Disease landscapes · 3 of 10 curated

Obesity (Metabolic & Nutrition)3 trials · 2 recruiting · 2 drugs0.3% of landscape
Type 2 diabetes (Endocrinology)2 trials · 1 recruiting · 1 drug0.2% of landscape
Alzheimer's disease (Neurology)1 trial · 1 recruiting · 1 drug0.3% of landscape

Active trials judged against ten curated disease boundaries; the share compares this company's active trials with the landscape's industry-wide total. Activity outside these landscapes appears in the therapy-area split above.

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We check every one of its trials daily and tell you what moved.

  • Status changeStatus moved to completedWas recruiting · always alerts
  • Completion date movePrimary completion slipped 210 daysSlips and pull-ins of 30+ days
  • New trialNew trial registered in your scopeFirst posted within 30 days
  • Enrollment changeEnrollment grew to 1,200Moves of 15%+ or count finalised
  • Substantive record editPrimary endpoint redefined from 24 to 52 weeksRead overnight and flagged in plain English
US registryClinicalTrials.gov
EU registryCTIS · Soon